Evidence map›Paper›PMID 36746635›Full record

ArticleNeurology2023

Changing Trends in Demographics, Risk Factors, and Clinical Features of Patients With Infective Endocarditis-Related Stroke, 2005-2015.

Mohamed Ridha, Mathew L Flaherty, Yasmin Aziz, Laura Ades, Kathleen Alwell, Jane C Khoury, Daniel Woo, Simona Ferioli, Opeolu Adeoye, Pooja Khatri and 15 more

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Article in Neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
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4citing papers in PubMed
–field-weighted citation impact
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4 citing papers in PubMed.

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25 authors.

Mohamed RidhaFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.). mridha@neomed.edu.
Mathew L FlahertyFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).
Yasmin AzizFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).ORCID 0000-0002-3515-4005
Laura AdesFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).
Kathleen AlwellFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).
Jane C KhouryFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).
Daniel WooFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).
Simona FerioliFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).
Opeolu AdeoyeFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).
Pooja KhatriFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).
Felipe De Los Rios La RosaFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).ORCID 0000-0003-4465-9280
Eva A MistryFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).
Stacie L DemelFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).
Jason MackeyFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).
Sharyl MartiniFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).
Elisheva ColemanFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).
Adam JasneFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).ORCID 0000-0001-9092-3607
Sabreena SlavinFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).
Kyle WalshFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).
Michael StarFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).
Mary HaverbuschFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).
Tracy E MadsenFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).
Joseph P BroderickFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).ORCID 0000-0002-7323-7709
Brett KisselaFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).ORCID 0000-0002-9773-4013
Dawn O KleindorferFrom the Columbia University Medical Center (M.R.), New York; University of Cincinnati Medical Center (M.R., M.L.F., Y.A., L.A., K.A., D.W., S.F., P.K., E.A.M., S.L.D., K.W., M.H., J.P.B., B.K., D.O.K.), OH; NYU Langone Hospital at Brooklyn (L.A.); Cincinnati Children's Hospital Medical Center (J.C.K.), OH; Washington University School of Medicine (O.A.), St. Louis, MO; Miami Neuroscience Institute (F.D.L.R.L.R.), Baptist Health South Florida, FL; Indiana University (J.M.), Indianapolis; VA National Telestroke Program (S.M.), Houston, TX; Northwestern University (E.C.), Chicago, IL; Yale University (A.J.), New Haven, CT; University of Kansas Medical Center (S.S.); Soroka Medical Center (M.S.), Beersheva, Israel; Brown University (T.E.M.), Providence, RI; and University of Michigan (D.O.K.).

Funding

STROKE INCIDENCE AND OUTCOME AMONG BLACKS AND WHITESR01NS030678 · NINDS · UNIVERSITY OF CINCINNATI · PI KISSELA, BRETT M, KLEINDORFER, DAWN O · 1993 to 2024
$26.7M
NINDS NIH HHS R01 NS030678
6 · The paper itself

Abstract

BACKGROUND AND

objectivesThere is a rising incidence of infective endocarditis-related stroke (IERS) in the United States attributed to the opioid epidemic. A contemporary epidemiologic description is necessary to understand the impact of the opioid epidemic on clinical characteristics of IERS. We describe and analyze trends in the demographics, risk factors, and clinical features of IERS.

methodsThis is a retrospective cohort study within a biracial population of 1.3 million in the Greater Cincinnati/Northern Kentucky region. All hospitalized patients with hemorrhagic or ischemic stroke were identified and physician verified from the 2005, 2010, and 2015 calendar years using ICD-9 and ICD-10 codes. IERS was defined as an acute stroke attributed to infective endocarditis meeting modified Duke Criteria for possible or definite endocarditis. Unadjusted comparison of demographics, risk factors, outcome, and clinical characteristics was performed between each study period for IERS and non-IERS. An adjusted model to compare trends used the Cochran-Armitage test for categorical variables and a general linear model or Kruskal-Wallis test for numerical variables. Examination for interaction of endocarditis status in trends was performed using a general linear or logistic model.

resultsA total of 54 patients with IERS and 8,204 without IERS were identified during the study periods. Between 2005 and 2015, there was a decline in rates of hypertension (91.7% vs 36.0%; DISCUSSION: From 2005 to 2015, IERS was increasingly associated with intravenous drug use and fewer risk factors, specifically hypertension. These trends likely reflect the demographics of the opioid epidemic, which has affected younger patients with fewer comorbidities.

Indexed as

EndocarditisHypertensionStrokeAnalgesics, OpioidDemographyHumansRetrospective StudiesRisk FactorsUnited StatesAnalgesics, Opioid

Identifiers

PMID36746635
PMCPMC10103121

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