ArticleBMJ open2023
Multimorbidity combinations and their association with functional disabilities among Indian older adults: evidence from Longitudinal Ageing Study in India (LASI).
Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 21 citations in OpenAlex.
- Self-medication among older adults in rural India: structural gaps in primary care and pain management.BMC health services research · 2026Article
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- Geriatric syndromes in elderly hospitalized patients in China: a cross-sectional study.Frontiers in medicine · 2026Article
- Burden of geriatric and cognitive disorders and the impact of integrated care models on morbidity, functional decline, and health service utilization among older adults.Frontiers in medicine · 2026Article
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- Examining the factors associated with disabilities among hypertensive patients in India.Narra J · 2025Article
- Interaction effect between sleep duration and dynapenic abdominal obesity for predicting functional disability: A longitudinal study.The journal of nutrition, health & aging · 2025Article
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- Association between urinary tract infections and anemia among the elderly in India: Insights from the longitudinal aging study.PLOS global public health · 2025Article
- Identifying multimorbidity risks in older adults: a cross-sectional study using the RGA screening data.Frontiers in public health · 2025Article
- Depressive symptoms and associated factors among older patients with arthritis: evidence from a community-based study in eastern China.Frontiers in public health · 2024Article
- Cardiometabolic multimorbidity in Mexican adults: a cross-sectional analysis of a national survey.Frontiers in medicine · 2024Article
- Overview of multimorbidity research in India: A scoping review.Journal of multimorbidity and comorbidityReview
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aims to identify the unique multimorbidity combinations (MMCs) and their associations with the functional disability of Indian older adults. Moreover, the population attributable fractions (PAFs) were calculated to assess the potential impact of additional diseases in the nested groups on disability.
designA cross-sectional data were analysed in this study. SETTING AND
participantsThe present study uses data from the first wave of the Longitudinal Ageing Study in India (2017-2018). The sample for the study consists of 27 753 aged 60 years and over. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome variable was functional disability, measured by the combined activities of daily living (ADL)-instrumental activities of daily living (IADL) index.
resultsOut of 197 uniquely identified MMCs, the combination of hypertension and high depressive symptoms (HDS) was the most prevalent (10.3%). Overall, all MMCs were associated with increased functional limitation. Specifically, the combination of hypertension, arthritis and HDS was associated with greater ADL-IADL disability than any other MMC. The addition of HDS in group 3 (hypertension and arthritis) (incidence rate ratios (IRR)=1.44; 95% CI 1.26 to 1.64) and the addition of arthritis in group 1 (hypertension, HDS) (IRR=1.48; 95% CI 1.28 to 1.71) and group 2 (hypertension, diabetes) (IRR=1.49; 95% CI 1.22 to 1.82) significantly increases the rates of ADL-IADL disability. The estimated PAFs of the group 1 (hypertension and HDS), group 3 (hypertension and arthritis) and group 4 (arthritis and HDS) for ADL-IADL disability were 22.5% (19.2-25.5), 21.6% (18.7-24.4) and 23.5% (20.6-26.3), respectively.
conclusionThe findings from this study underscore the importance of addressing the morbidity combinations which are more disabling than the others in older adults. Understanding the somatic and psychological relevance of the morbidities in functional health is necessary and can help reduce disabilities among older adults.
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