Evidence map›Paper›PMID 36745790›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Palmitoylation of the pore-forming subunit of Ca(v)1.2 controls channel voltage sensitivity and calcium transients in cardiac myocytes.

Chien-Wen S Kuo, Sara Dobi, Caglar Gök, Ana Da Silva Costa, Alice Main, Olivia Robertson-Gray, Daniel Baptista-Hon, Krzysztof J Wypijewski, Hannah Costello, Tim G Hales and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Palmitoylation in cardiovascular diseases: Molecular mechanism and therapeutic potential.International journal of cardiology. Heart & vasculature · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Topology-Driven Discovery of Transmembrane ProteinbioRxiv : the preprint server for biology · 2024
    Article
  10. Mechanisms and functions of protein S-acylation.Nature reviews. Molecular cell biology · 2024
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Chien-Wen S KuoSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow G12 8QQ, UK.ORCID 0000-0002-1903-7618
Sara DobiSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow G12 8QQ, UK.
Caglar GökSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow G12 8QQ, UK.ORCID 0000-0002-2145-0057
Ana Da Silva CostaSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow G12 8QQ, UK.ORCID 0000-0003-3229-5424
Alice MainSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow G12 8QQ, UK.ORCID 0000-0003-4094-2740
Olivia Robertson-GraySchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow G12 8QQ, UK.
Daniel Baptista-HonDivision of Systems Medicine, Institute of Academic Anaesthesia, School of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.ORCID 0000-0002-5358-1035
Krzysztof J WypijewskiSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow G12 8QQ, UK.ORCID 0000-0002-6093-9429
Hannah CostelloDivision of Systems Medicine, Institute of Academic Anaesthesia, School of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.ORCID 0000-0002-9655-3798
Tim G HalesDivision of Systems Medicine, Institute of Academic Anaesthesia, School of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.ORCID 0000-0002-2040-9714
Niall MacQuaideSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow G12 8QQ, UK.ORCID 0000-0001-9026-0073
Godfrey L SmithSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow G12 8QQ, UK.
William FullerSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow G12 8QQ, UK.ORCID 0000-0002-5883-4433
University of Glasgow · GBUniversity of Dundee · GBGlasgow Caledonian University · GBMacau University of Science and Technology · MO

Funding

British Heart Foundation PG/16/33/32134British Heart Foundation PG/18/60/33957British Heart Foundation PG/19/5/34150British Heart Foundation PG/21/10363British Heart Foundation PG/22/10847British Heart Foundation SP/16/3/32317
6 · The paper itself

Abstract

Mammalian voltage-activated L-type Ca

Indexed as

Induced Pluripotent Stem CellsMyocytes, CardiacAnimalsCalciumCalcium Channels, L-TypeCalcium, DietaryHumansLipoylationMammalsRabbitsRatsCalciumCalcium Channels, L-TypeCalcium, Dietaryacylationexcitation–contraction couplingheartion transport

Identifiers

PMID36745790
PMCPMC9963536
OpenAlexW4319302443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.