Evidence map›Paper›PMID 36745620›Full record

ArticlePloS one2023

Protocol for the systematic review and meta-analysis of factors associated with non-adherence to antidepressants in depressive disorders in those more than 18 years of age.

Saraswati Dhungana, Rojal Rijal, Binit Regmi, Jala Shree Bajracharya, Subriddhi Sharma, Sunil Singh, Nilam Karn, Manisha Chapagai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Saraswati DhunganaDepartment of Psychiatry and Mental Health, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal.ORCID 0000-0002-9727-4723
Rojal RijalChitwan Medical College, Bharatpur, Nepal.
Binit RegmiNepalese Army Institute of Health Sciences, Kathmandu, Nepal.
Jala Shree BajracharyaWeifang Medical University, Weifang, China.
Subriddhi SharmaCollege of Medical Sciences, Bharatpur, Nepal.
Sunil SinghWeifang Medical University, Weifang, China.
Nilam KarnKoshi Hospital, Biratnagar, Nepal.
Manisha ChapagaiDepartment of Psychiatry and Mental Health, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal.
Tribhuvan University · NPWeifang Medical University · CNBiratnagar Eye Hospital · NPChitwan Medical College · NPCollege of Medical Sciences · NPNepalese Army Institute of Health Services · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe have developed a protocol for the systematic review and meta-analysis of the factors associated with nonadherence to antidepressants in depressive patients more than 18 years of age.

methodsWe will search articles with the databases PubMed- Medline, Scopus, Embase and PsychINFO. All the published literature reporting factors associated with nonadherence to antidepressants in depressive disorders in patients more than 18 years of age and fulfilling all the eligibility criteria till October 2022 will be included. The data will then be extracted and examined to be included in the systematic review. Finally, we will conduct meta-analysis for factors associated with non-adherence.

conclusionWe will do extensive search on the proposed topic within the available literature and come up with a robust review of factors associated with nonadherence to antidepressants in patients age more than 18 years globally. The evidence generated would assist in designing interventions to address non-adherence in this group of patients leading to better productivity and quality of life.

Indexed as

Depressive DisorderQuality of LifeAdolescentAntidepressive AgentsDepressionHumansMeta-Analysis as TopicSystematic Reviews as TopicAntidepressive Agents

Identifiers

PMID36745620
PMCPMC9901773
OpenAlexW4319295039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.