Evidence map›Paper›PMID 36745547›Full record

ArticleOncotarget2023

Everolimus downregulates STAT3/HIF-1α/VEGF pathway to inhibit angiogenesis and lymphangiogenesis in

Md Maksudul Alam, Janmaris Marin Fermin, Mark Knackstedt, Mackenzie J Noonan, Taylor Powell, Landon Goodreau, Emily K Daniel, Xiaohua Rong, Tara Moore-Medlin, Alok R Khandelwal and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  4. Review
  5. Erbin Inhibited AngiogenesisCurrent medicinal chemistry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Md Maksudul AlamDepartment of Otolaryngology-Head and Neck Surgery, LSU-Health Sciences Center, Shreveport, LA 71103, USA.
Janmaris Marin FerminDepartment of Otolaryngology-Head and Neck Surgery, LSU-Health Sciences Center, Shreveport, LA 71103, USA.
Mark KnackstedtDepartment of Otolaryngology-Head and Neck Surgery, LSU-Health Sciences Center, Shreveport, LA 71103, USA.
Mackenzie J NoonanDepartment of Otolaryngology-Head and Neck Surgery, LSU-Health Sciences Center, Shreveport, LA 71103, USA.
Taylor PowellSchool of Medicine, LSU-Health Sciences Center, Shreveport, LA 71103, USA.
Landon GoodreauSchool of Medicine, LSU-Health Sciences Center, Shreveport, LA 71103, USA.
Emily K DanielDepartment of Otolaryngology-Head and Neck Surgery, LSU-Health Sciences Center, Shreveport, LA 71103, USA.
Xiaohua RongDepartment of Otolaryngology-Head and Neck Surgery, LSU-Health Sciences Center, Shreveport, LA 71103, USA.
Tara Moore-MedlinDepartment of Otolaryngology-Head and Neck Surgery, LSU-Health Sciences Center, Shreveport, LA 71103, USA.
Alok R KhandelwalDepartment of Otolaryngology-Head and Neck Surgery, LSU-Health Sciences Center, Shreveport, LA 71103, USA.
Cherie-Ann O NathanDepartment of Otolaryngology-Head and Neck Surgery, LSU-Health Sciences Center, Shreveport, LA 71103, USA.
Louisiana State University Health Sciences Center Shreveport · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EverolimusHead and Neck NeoplasmsAnimalsCell Line, TumorHumansHypoxia-Inducible Factor 1, alpha SubunitLymphangiogenesisMiceMice, NudeNeovascularization, PathologicSquamous Cell Carcinoma of Head and NeckSTAT3 Transcription FactorTOR Serine-Threonine KinasesTumor Suppressor Protein p53Vascular Endothelial Growth Factor AEverolimusHypoxia-Inducible Factor 1, alpha SubunitSTAT3 protein, humanSTAT3 Transcription FactorTOR Serine-Threonine KinasesTP53 protein, humanTumor Suppressor Protein p53Vascular Endothelial Growth Factor AangiogenesiseverolimusHNSCCmTORTP53 mutant

Identifiers

PMID36745547
PMCPMC9901561
OpenAlexW4318994294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.