Evidence map›Paper›PMID 36745536›Full record

ArticleJournal of the American Chemical Society2023

Red-Shifted Coumarin Luciferins for Improved Bioluminescence Imaging.

Anna C Love, Donald R Caldwell, Bethany Kolbaba-Kartchner, Katherine M Townsend, Lila P Halbers, Zi Yao, Caroline K Brennan, Joseph Ivanic, Tanya Hadjian, Jeremy H Mills and 2 more

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
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  5. Article
  6. The latest developments of near-infrared fluorescent probes from NIR-I to NIR-II for bioimaging.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Review
  7. Article
  8. Article
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  12. Review
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Anna C LoveDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.
Donald R CaldwellChemical Biology Laboratory, Cancer for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland 21702, United States.ORCID 0000-0002-6023-3733
Bethany Kolbaba-KartchnerSchool of Molecular Sciences, Arizona State University, Tempe, Arizona 85281, United States.
Katherine M TownsendDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.
Lila P HalbersDepartment of Pharmaceutical Sciences, University of California, Irvine, Irvine, California 92697, United States.
Zi YaoDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.
Caroline K BrennanDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.
Joseph IvanicAdvanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, Maryland 21702, United States.ORCID 0000-0003-2104-7169
Tanya HadjianDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.ORCID 0000-0001-8194-4043
Jeremy H MillsSchool of Molecular Sciences, Arizona State University, Tempe, Arizona 85281, United States.ORCID 0000-0003-2017-1846
Martin J SchnermannChemical Biology Laboratory, Cancer for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland 21702, United States.ORCID 0000-0002-0503-0116
Jennifer A PrescherDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.ORCID 0000-0002-9250-4702

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
Synthesis and evaluation of small-molecule imaging agentsZIABC011506 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI SCHNERMANN, MARTIN · 2013 to 2025
$12.1M
purchase of an All-in-One Fluorescence MicroscopeR01GM107630 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI PRESCHER, JENNIFER · 2013 to 2021
$2.6M
New tools for quantitative non-invasive recording of biochemical signalsR01CA279813 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jennifer Prescher, Nathan Christopher Shaner · 2024 to 2026
$2.0M
CCR NIH HHS HHSN261200800001CNCI NIH HHS HHSN261200800001ENCI NIH HHS P30 CA062203NCI NIH HHS R01 CA279813NIGMS NIH HHS R01 GM107630
6 · The paper itself

Abstract

Multicomponent bioluminescence imaging

Indexed as

Firefly LuciferinLuciferinsCoumarinsLuciferasesLuminescent MeasurementsCoumarinsFirefly LuciferinLuciferasesLuciferins

Identifiers

PMID36745536
PMCPMC10519142

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.