ReviewReviews in endocrine & metabolic disorders2023
The use of phase angle in patients with digestive and liver diseases.
Review in Reviews in endocrine & metabolic disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Differential predictive value of phase angle for malnutrition and physical impairment in respiratory patients: the moderating role of sarcopenia.Frontiers in nutrition · 2026Article
- Bioelectrical impedance-derived phase angle as a contextual indicator for steatotic liver disease and hepatic fat estimation.Frontiers in nutrition · 2026Article
- Analysis of factors influencing the increase of extracellular water ratio in tumor patients without edema signs.Frontiers in medicine · 2025Article
- Phase angle associates with severity and mortality in acute-on-chronic liver failure.Frontiers in medicine · 2025Article
- Increased BMI favors weaning in patients with chronic intestinal failure due to short bowel syndrome: a retrospective cohort study in Italy.Frontiers in nutrition · 2025Article
- Phase Angle (PhA) Is an Easy and Complementary Tool for Assessing Nutritional Status in Ulcerative Colitis (UC) Patients: A Cross-Sectional Study.Life (Basel, Switzerland) · 2024Article
- Quantitative Assessment of Body Composition in Cirrhosis.Diagnostics (Basel, Switzerland) · 2024Review
- Association between Physical Activity and Phase Angle Obtained via Bioelectrical Impedance Analysis in South Korean Adults Stratified by Sex.Nutrients · 2024Article
- Article
- Phase angle in applications of bioimpedance in health and disease.Reviews in endocrine & metabolic disorders · 2023Review
- Future lines of research on phase angle: Strengths and limitations.Reviews in endocrine & metabolic disorders · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diseases of the liver and the digestive system can lead to malnutrition through an action of reduced food intake or nutrient use, inflammation and impaired metabolism, which result in substantial changes in body composition. Frequently, malnutrition manifests itself with weight loss and reduced muscle mass. However, weight loss and body mass index lack sensitivity to detect the loss of muscle mass and are not informative in distinguishing body water compartments and in characterizing their distribution. This issue is particularly relevant to these two disease models, which are frequently associated with fluid volume imbalances. Phase angle is a useful indicator for cell membrane integrity, water distribution between the intracellular and extracellular spaces and prediction of body cell mass as it is described by measured components of electrical impedance. Malnutrition, inflammation and oxidative stress impair electric tissue properties leading to lower values of PhA. In patients with inflammatory bowel and liver diseases, PhA was consistently found to be related to nutritional status and body composition, particularly the depletion of lean body mass and sarcopenia. It has been associated with prognosis, disease stage and severity and found to be helpful in monitoring fluid shifts and response to interventions.
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Registered trials
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