Evidence map›Paper›PMID 36745315›Full record

ArticleOphthalmology and therapy2023

Association of Poor Quality of Sleep with Vision-Threatening Diabetic Retinopathy: A Matched Case-Control Study.

Getasew Alemu Mersha, Destaye Shiferaw Alemu, Meneberesibhat Getie Ferede, Melkamu Temeselew Tegegn, Mikias Mered Tilahun, Merkineh Markos Lorato, Biruk Lelisa Eticha, Asamere Tsegaw Woredekal

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ophthalmology and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Getasew Alemu MershaDepartment of Optometry, School of Medicine, University of Gondar Comprehensive and Specialized Hospital, Gondar, Ethiopia. gechopta12@gmail.com.ORCID http://orcid.org/0000-0002-9996-8032
Destaye Shiferaw AlemuDepartment of Optometry, School of Medicine, University of Gondar Comprehensive and Specialized Hospital, Gondar, Ethiopia.
Meneberesibhat Getie FeredeDepartment of Human Anatomy, University of Gondar Comprehensive and Specialized Hospital, Gondar, Ethiopia.
Melkamu Temeselew TegegnDepartment of Optometry, School of Medicine, University of Gondar Comprehensive and Specialized Hospital, Gondar, Ethiopia.
Mikias Mered TilahunDepartment of Optometry, School of Medicine, University of Gondar Comprehensive and Specialized Hospital, Gondar, Ethiopia.
Merkineh Markos LoratoDepartment of Optometry, School of Medicine, University of Gondar Comprehensive and Specialized Hospital, Gondar, Ethiopia.
Biruk Lelisa EtichaDepartment of Optometry, School of Medicine, University of Gondar Comprehensive and Specialized Hospital, Gondar, Ethiopia.
Asamere Tsegaw WoredekalDepartment of Ophthalmology, School of Medicine, University of Gondar Comprehensive and Specialized Hospital, Gondar, Ethiopia.
University of Gondar · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionVision-threatening diabetic retinopathy, a long-term microvascular complication of diabetes in the eye, is a major cause of blindness worldwide. Sleep is regulated by a special area of the brain, and poor quality of sleep has been implicated in long-term diabetic complications, including diabetic retinopathy. The study was aimed at exploring whether poor sleep quality is associated with the likelihood of developing vision-threatening diabetic retinopathy.

methodsA matched case-control study was conducted from 6 May 2022 to 6 September 2022. The study was based on patients with diabetes (both type 1 and type 2), attending a retina clinic of the referral center. Patients with confirmed vision-threatening diabetic retinopathy were defined as cases and matched with control study subjects. Rating of sleep quality was done by Pittsburgh Sleep Quality Index assessment tool. Conditional logistic regression model was applied to assess the effect of overall poor sleep quality on vision-threatening diabetic retinopathy.

resultsThe study recruited a total of 126 (63 duration-matched pairs) patients with diabetes. The overall quality of sleep was poor among 71.90% of patients in the case groups, significantly higher compared with those of the control groups (28.10%) (p < 0.00). The mean quality of sleep for cases [mean (M) = 7.10, standard deviation (SD) = 4.30] was higher than the control group (M = 3.60, SD = 2.70). The magnitude of the difference [M difference = 3.50, 95% confidence interval (CI): 2.25-4.75] was significant. Poor sleep quality predicted the chance of developing vision-threatening diabetic retinopathy in a diabetic cohort.

conclusionsThis study revealed a significant association between the overall poor quality of sleep and vision-threatening diabetic retinopathy. Co-management of sleep disruption and vision-threatening diabetic retinopathy, and better sleep advisory are warranted.

Indexed as

Patients with diabetesPittsburgh Sleep Quality Index questionnairePoor sleep qualityVision-threatening diabetic retinopathy

Identifiers

PMID36745315
PMCPMC10011256
OpenAlexW4319294858

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.