Evidence map›Paper›PMID 36745207›Full record

ArticleAbdominal radiology (New York)2023

The usefulness of preoperative CT in colon cancer staging: impact of radiologists' experience.

Davide Ippolito, Cesare Maino, Ilaria Bianco, Silvia Girolama Drago, Raffaella Piazza, Nicolo Tamini, Luca Nespoli, Teresa Giandola, Sandro Sironi

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In one paragraph

Article in Abdominal radiology (New York), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Davide IppolitoDepartment of Diagnostic Radiology, Fondazione IRCCS San Gerardo Dei Tintori, Via Pergolesi 33, 20900, Monza, MB, Italy.
Cesare MainoDepartment of Diagnostic Radiology, Fondazione IRCCS San Gerardo Dei Tintori, Via Pergolesi 33, 20900, Monza, MB, Italy. mainocesare@gmail.com.ORCID http://orcid.org/0000-0002-5742-802X
Ilaria BiancoDepartment of Diagnostic Radiology, Fondazione IRCCS San Gerardo Dei Tintori, Via Pergolesi 33, 20900, Monza, MB, Italy.
Silvia Girolama DragoDepartment of Diagnostic Radiology, Fondazione IRCCS San Gerardo Dei Tintori, Via Pergolesi 33, 20900, Monza, MB, Italy.
Raffaella PiazzaDepartment of Diagnostic Radiology, Fondazione IRCCS San Gerardo Dei Tintori, Via Pergolesi 33, 20900, Monza, MB, Italy.
Nicolo TaminiSchool of Medicine, University of Milano Bicocca, Via Cadore 33, 20090, Monza, MB, Italy.
Luca NespoliSchool of Medicine, University of Milano Bicocca, Via Cadore 33, 20090, Monza, MB, Italy.
Teresa GiandolaDepartment of Diagnostic Radiology, Fondazione IRCCS San Gerardo Dei Tintori, Via Pergolesi 33, 20900, Monza, MB, Italy.
Sandro SironiSchool of Medicine, University of Milano Bicocca, Via Cadore 33, 20090, Monza, MB, Italy.
Azienda Ospedaliera San Gerardo · ITOspedale Papa Giovanni XXIII · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the agreement between radiologists in the detection of specific features related to T- and N-stage and evaluate accuracy in colon cancer staging.

methodsPatients who underwent contrast-enhanced computed tomography (CECT) before surgery were enrolled and evaluated by three radiologists with different experience. Pathological data were used as the reference standard. Tumor location, presence of tumor bulging, fat stranding, lateroconal fascia invasion, enlarged vessels, axial short diameter of the biggest node, shape, enhancement pattern, intranodal necrosis, and cluster were collected. Reliability analysis was performed with κ statistics and intraclass correlation coefficients (ICCs). Logistic regressions were used to determine independent predictors associated with staging.

resultsSeventy five patients were evaluated. The reliability analysis was moderate to substantial for tumor location (κ = 0.853), T staging (κ = 0.531), tumor bulging (κ = 0.478), fat stranding (κ = 0.490), lateroconal fascia invasion (κ = 0.436), enlarged vessels (κ = 0.401), the axial short diameter of the biggest node (ICC = 0.732), shape (κ = 0.484), enhancement pattern (κ = 0.431), intranodal necrosis (κ = 0.606), and cluster (κ = 0.358). For all readers, sensitivity was higher for T3 lesions (60-69%) and specificity was higher for T2 and T4 lesions (84.5-90.0% and 82.4-85.1%). The diagnostic accuracy was acceptable for all lesions and among all readers (50.7-92.1%). The lateroconal fascia invasion and enlarged vessels resulted as independent predictor factors (OR = 3.292 and OR = 2.651) for T staging, while nodes' cluster and dimension as independent predictor factors of N staging [OR = 3.798 and OR = 1.083].

conclusionReader's experience is one of the most important factors associated with the correct classification of colon cancer. Moreover, CECT can help depict radiological features independently associated with the T and N stages.

Indexed as

Colonic NeoplasmsHumansNeoplasm StagingRadiologistsReproducibility of ResultsSensitivity and SpecificityTomography, X-Ray ComputedColon cancerData accuracyStagingTomographyX-Ray computed

Identifiers

PMID36745207
OpenAlexW4319293872

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.