Evidence map›Paper›PMID 36745147›Full record

ArticleProceedings of the ... IAPR International Conference on Pattern Recognition. International Conference on Pattern Recognition2021

Classifying Breast Histopathology Images with a Ductal Instance-Oriented Pipeline.

Beibin Li, Ezgi Mercan, Sachin Mehta, Stevan Knezevich, Corey W Arnold, Donald L Weaver, Joann G Elmore, Linda G Shapiro

Abstract read
In one paragraph

Article in Proceedings of the ... IAPR International Conference on Pattern Recognition. International Conference on Pattern Recognition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Beibin LiUniversity of Washington, Seattle, WA.
Ezgi MercanSeattle Children's Hospital, Seattle, WA.
Sachin MehtaUniversity of Washington, Seattle, WA.
Stevan KnezevichPathology Associates, Clovis, CA.
Corey W ArnoldUniversity of California, Los Angles, CA.
Donald L WeaverUniversity of Vermont, Burlington, VT.
Joann G ElmoreUniversity of California, Los Angles, CA.
Linda G ShapiroUniversity of Washington, Seattle, WA.

Funding

Accuracy of Breast Pathology and the Impact of Double ReadingR01CA140560 · NCI · UNIVERSITY OF WASHINGTON · PI ELMORE, JOANN G, WEAVER, DONALD LEE · 2009 to 2013
$3.3M
Digital Pathology_Accuracy Viewing Behavior and Image CharacterizationR01CA172343 · NCI · UNIVERSITY OF WASHINGTON · PI SHAPIRO, LINDA, WEAVER, DONALD LEE · 2013 to 2017
$3.2M
Improving Melanoma Pathology Accuracy through Computer Vision Techniques - the IMPACT StudyR01CA200690 · NCI · UNIVERSITY OF WASHINGTON · PI ELMORE, JOANN G, SHAPIRO, LINDA · 2016 to 2020
$1.9M
A Unified Machine Learning Package for Cancer DiagnosisU01CA231782 · NCI · UNIVERSITY OF WASHINGTON · PI ELMORE, JOANN G, SHAPIRO, LINDA · 2018 to 2020
$980k
NCI NIH HHS R01 CA140560NCI NIH HHS R01 CA172343NCI NIH HHS R01 CA200690NCI NIH HHS U01 CA231782
6 · The paper itself

Abstract

In this study, we propose the Ductal Instance-Oriented Pipeline (DIOP) that contains a duct-level instance segmentation model, a tissue-level semantic segmentation model, and three-levels of features for diagnostic classification. Based on recent advancements in instance segmentation and the Mask RCNN model, our duct-level segmenter tries to identify each ductal individual inside a microscopic image; then, it extracts tissue-level information from the identified ductal instances. Leveraging three levels of information obtained from these ductal instances and also the histopathology image, the proposed DIOP outperforms previous approaches (both feature-based and CNN-based) in all diagnostic tasks; for the four-way classification task, the DIOP achieves comparable performance to general pathologists in this unique dataset. The proposed DIOP only takes a few seconds to run in the inference time, which could be used interactively on most modern computers. More clinical explorations are needed to study the robustness and generalizability of this system in the future.

Indexed as

biomedical imagingbiopsycancer diagnosisdeep learninghistopathologymachine learningwhole slide images

Identifiers

PMID36745147
PMCPMC9893896

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.