Evidence map›Paper›PMID 36745097›Full record

ArticleJournal of feline medicine and surgery2023

Symblepharon in kittens: a retrospective study of 40 kittens and 54 eyes (2002-2022).

Hikaru Shiraishi, Karen M Vernau, Soohyun Kim, Kathryn L Good, Steven R Hollingsworth, Lionel Sebbag, Elizabeth Montgomery, Jennifer D Surmick, Kate S Freeman, Eunju Choi and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Hikaru ShiraishiSchool of Veterinary Medicine, University of California Davis, Davis, CA, USA.ORCID 0000-0002-9613-9933
Karen M VernauSurgical and Radiological Sciences, University of California Davis, Davis, CA, USA.
Soohyun KimWilliam R Pritchard Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA, USA.
Kathryn L GoodSchool of Veterinary Medicine, University of California Davis, Davis, CA, USA.
Steven R HollingsworthSchool of Veterinary Medicine, University of California Davis, Davis, CA, USA.
Lionel SebbagCollege of Veterinary Medicine, Iowa State University, Ames, IA, USA.ORCID 0000-0002-0103-0127
Elizabeth MontgomerySchool of Veterinary Medicine, University of California Davis, Davis, CA, USA.
Jennifer D SurmickSchool of Veterinary Medicine, University of California Davis, Davis, CA, USA.
Kate S FreemanVeterinary Vision, San Francisco, CA, USA.
Eunju ChoiSchool of Veterinary Medicine, University of California Davis, Davis, CA, USA.
M Isabel CasanovaSchool of Veterinary Medicine, University of California Davis, Davis, CA, USA.
David J MaggsSchool of Veterinary Medicine, University of California Davis, Davis, CA, USA.ORCID 0000-0001-6537-4335
University of California, Davis · USIowa State University · USVeterinary Medical Teaching Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to retrospectively evaluate the signalment, treatment, surgical technique and outcomes for feline symblepharon.

methodsA retrospective medical record review and standardized grading of clinical descriptions and photographs was undertaken.

resultsForty kittens (54 eyes) aged 3-46 weeks had symblepharon of five types in various combinations: eyelid deformation (24 kittens; 32 eyes); ankyloblepharon (four kittens; four eyes); conjunctiva-to-conjunctiva (11 kittens; 12 eyes); third eyelid-to-conjunctiva (24 kittens; 29 eyes); and corneoconjunctival adhesions (14 kittens; 16 eyes). At initial presentation, 23 (43%) eyes were affected by one type of symblepharon, 25 (46%) eyes by two types and six (11%) eyes by three types; 11 (20%) corneas were ulcerated. Twenty-four (44%) eyes of 18 (45%) kittens were managed medically. Surgery was performed under general anesthesia/sedation (30 occasions) or topical anesthesia (21 occasions) on 30 (56%) eyes of 22 kittens; 12 eyes (40%) underwent multiple surgeries. Four techniques were commonly employed: separation of conjunctival-to-conjunctival adhesions ± eyelid margins (14 eyes); resection of third eyelid adhesions ± temporary tacking of the third eyelid (modified Arlt's pterygium technique; 18 eyes); en bloc resection of the third eyelid (two eyes); and separation of corneoconjunctival adhesions (14 eyes). Median duration of follow-up was 55 days (range 1-1051). Median symblepharon grade in kittens treated surgically improved for all types except corneoconjunctival symblepharon. Median symblepharon grade in kittens receiving medical management remained the same or improved. Corneoconjunctival symblepharon opacity decreased for eyes treated surgically but increased for eyes treated medically. Three eyes were enucleated due to complications of corneoconjunctival symblepharon. At final presentation, symblepharon persisted in 46 (85%) eyes; however, menace response was evident in 13/16 eyes and dazzle reflex in 23/23 eyes. CONCLUSIONS AND RELEVANCE: Symblepharon is a heterogeneous group of conditions with diverse anatomic involvement, clinical appearance and impact, optimal treatment and prognosis for vision.

Indexed as

Cat DiseasesEyelid DiseasesPterygiumAnimalsCatsConjunctivaFemaleRetrospective Studiesadhesionsconjunctival ulcercorneal ulcerFeline herpesvirusophthalmologysurgery

Identifiers

PMID36745097
PMCPMC10812067
OpenAlexW4319294635

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.