Evidence map›Paper›PMID 36745039›Full record

ArticleInflammatory bowel diseases2023

Treatment of Chronic Inflammatory Pouch Conditions With Tofacitinib: A Case Series From 2 Tertiary IBD Centers in the United States.

Shintaro Akiyama, Nathaniel A Cohen, Maia Kayal, Marla C Dubinsky, Jean-Frederic Colombel, David T Rubin

Registry-linked trialAbstract read
In one paragraph

Article in Inflammatory bowel diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06864403 (Mirikizumab in the Treatment of Chronic Inflammatory Conditions of the Pouch), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06864403 phase4recruitingnot on this mapstarted 2025, after this paper: background citation

Mirikizumab in the Treatment of Chronic Inflammatory Conditions of the Pouch

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2025 to 2027Enrolled25ConditionsPouchitis, Pouches, Ileoanal, Pouch, IlealArmsMirikizumab - Intravenous (IV), Mirikizumab - Subcutaneous (SC)
3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Tofacitinib for the treatment of chronic pouchitis: A pilot study.United European gastroenterology journal · 2025
    Article
  6. Review
  7. Approach to Therapy for Chronic Pouchitis.Annual review of medicine · 2025
    Review
  8. Review
  9. Review
  10. Pouchitis: pathophysiology and management.Nature reviews. Gastroenterology & hepatology · 2024
    Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shintaro AkiyamaInflammatory Bowel Disease Center, University of Chicago Medicine, Chicago, IL, USA.
Nathaniel A CohenInflammatory Bowel Disease Center, University of Chicago Medicine, Chicago, IL, USA.
Maia KayalDivision of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-9640-950X
Marla C DubinskyDivision of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jean-Frederic ColombelDivision of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0001-6472-249X
David T RubinInflammatory Bowel Disease Center, University of Chicago Medicine, Chicago, IL, USA.ORCID 0000-0001-5647-1723

Funding

ULTRASTRUCTURE AND CYTOMORPHOLOGY COREP30DK042086 · NIDDK · UNIVERSITY OF CHICAGO · PI ABADIE, VALERIE · 1990 to 2025
$29.8M
Host and microbial basis of human ulcerative colitis and pouchitis: Identification, role, mechanisms, and resource development of host susceptibility and pathobiont factorsRC2DK122394 · NIDDK · UNIVERSITY OF CHICAGO · PI CHANG, EUGENE B · 2019 to 2023
$10.2M
Characterizing the Biologic Evolution of Crohn's Disease Like Pouch Inflammation in Ulcerative Colitis Patients After Restorative Proctocolectomy with Ileal Pouch Anal AnastomosisK23DK127241 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Maia Kayal · 2022 to 2026
$955k
NIDDK NIH HHS K23 DK127241NIDDK NIH HHS P30 DK042086NIDDK NIH HHS RC2 DK122394
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Colitis, UlcerativeColonic PouchesCrohn DiseasePouchitisProctocolectomy, RestorativeHumansPiperidinesPyrimidinesUnited StatesPiperidinesPyrimidinestofacitinibchronic pouchitisCrohn's disease–like pouch inflammationtofacitinib

Identifiers

PMID36745039
PMCPMC10472733

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.