Evidence map›Paper›PMID 36744913›Full record

ArticleEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2023

Hydrodynamic ex vivo analysis of valve-sparing techniques: assessment and comparison.

Sofia Di Leonardo, Danila Vella, Carmelo Savio Grillo, Carla Martorana, Salvatore Torre, Vincenzo Argano, Gaetano Burriesci

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Article in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Sofia Di LeonardoBioengineering Group, Ri.MED Foundation, Palermo, Italy.ORCID 0000-0003-0689-1396
Danila VellaBioengineering Group, Ri.MED Foundation, Palermo, Italy.ORCID 0000-0001-6251-3651
Carmelo Savio GrilloSchool of Medicine and Surgery, University of Palermo, Palermo, Italy.
Carla MartoranaSchool of Medicine and Surgery, University of Palermo, Palermo, Italy.
Salvatore TorreSchool of Medicine and Surgery, University of Palermo, Palermo, Italy.ORCID 0000-0002-0711-1067
Vincenzo ArganoSchool of Medicine and Surgery, University of Palermo, Palermo, Italy.
Gaetano BurriesciBioengineering Group, Ri.MED Foundation, Palermo, Italy.ORCID 0000-0002-9213-3403

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesValve-sparing procedures are surgical techniques allowing to restore adequate function of the native aortic valve by replacing the dysfunctional ascending aorta with a prosthetic conduit. A number of techniques are currently used, such as Yacoub's remodelling and David's reimplantation, based on a regular straight conduit. More recently, the De Paulis proposed the use of bulging conduits to reconstruct the shape of the Valsalva sinuses. This work investigates the impact of the valve-sparing technique on the aortic valve function.

methodsThe performance of 3 porcine aortic roots (Medtronic Freestyle™) was assessed in a cardiovascular pulse duplicator before and after performing 3 alternative valve-sparing procedures: David's reimplantation, Yacoub's remodelling and De Paulis' reimplantation.

resultsThe porcine aortic roots, representative of the healthy native configuration, were characterized by the highest efficiency, with a mean energetic dissipation under normal operating conditions of 26 mJ. David's and Yacoub's techniques resulted in significantly lower performance (with mean energetic loss of about 70 mJ for both cases). The De Paulis' procedure exhibited intermediate behaviour, with superior systolic performance and valve dynamics similar to the native case, and a mean energetic loss of 38 mJ.

conclusionsThe dynamics and performance after valve-sparing strongly depend on the adopted technique, with the use of conduits replicating the presence of Valsalva sinuses restoring more physiological conditions.

Indexed as

Aortic Valve InsufficiencySinus of ValsalvaAnimalsAortaAortic ValveHydrodynamicsSwineAortic root prosthesisEx vivo analysisHydrodynamic performanceValsalva sinusesValve-sparing implants

Identifiers

PMID36744913
PMCPMC10049755

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.