Evidence map›Paper›PMID 36744734›Full record

ArticleBiomaterials science2023

Linear and nonlinear rheology of liberase-treated breast cancer tumors.

Ria D Corder, Robert B Vachieri, Megan E Martin, Darlene K Taylor, Jodie M Fleming, Saad A Khan

Open access · greenAbstract read
In one paragraph

Article in Biomaterials science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ria D CorderDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC, 27695, USA. khan@eos.ncsu.edu.ORCID http://orcid.org/0000-0001-6078-2233
Robert B VachieriDepartment of Chemistry and Biochemistry, North Carolina Central University, Durham, NC, 27707, USA.
Megan E MartinDepartment of Biological and Biomedical Sciences, North Carolina Central University, Durham, NC, 27707, USA. jodie.fleming@nih.gov.
Darlene K TaylorDepartment of Chemistry and Biochemistry, North Carolina Central University, Durham, NC, 27707, USA.ORCID http://orcid.org/0000-0002-6348-8336
Jodie M FlemingDepartment of Biological and Biomedical Sciences, North Carolina Central University, Durham, NC, 27707, USA. jodie.fleming@nih.gov.ORCID http://orcid.org/0000-0003-0297-5197
Saad A KhanDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC, 27695, USA. khan@eos.ncsu.edu.ORCID http://orcid.org/0000-0002-1530-8249
North Carolina Central University · USNorth Carolina State University · US

Funding

Engineering novel methods to study metastases and reduce systemic treatment toxicity in breast cancer patientsR15CA223994 · NCI · NORTH CAROLINA CENTRAL UNIVERSITY · PI TAYLOR, DARLENE KIMBER, WILLIAMS, KEVIN PETER · 2019 to 2019
$444k
NCI NIH HHS R15 CA223994
6 · The paper itself

Abstract

Extracellular matrix (ECM) rigidity has been shown to increase the invasive properties of breast cancer cells, promoting transformation and metastasis through mechanotransduction. Reducing ECM stiffness

Indexed as

Mechanotransduction, CellularNeoplasmsAnimalsCollagenasesMiceRheologyThermolysinCollagenasesLiberaseThermolysin

Identifiers

PMID36744734
PMCPMC10023448
OpenAlexW4318617679

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.