Evidence map›Paper›PMID 36744726›Full record

ArticleMagnetic resonance in medicine2023

In vivo reproducibility of 3D relayed NOE in the healthy human brain at 7 T.

Blake Benyard, Ravi Prakash Reddy Nanga, Neil E Wilson, Deepa Thakuri, Paul S Jacobs, Anshuman Swain, Dushyant Kumar, Ravinder Reddy

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Multimodal MR Imaging for quantification of brain lipid in mice at 9.4T.bioRxiv : the preprint server for biology · 2025
    Article
  5. In Vivo Brain BNMR in biomedicine · 2025
    Article
  6. Article
  7. iScience · 2024
    Article
  8. Early-stage mapping of macromolecular content in APPFrontiers in aging neuroscience · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Blake BenyardCenter for Metabolic Imaging in Precision Medicine (CAMIPM), Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-2480-4164
Ravi Prakash Reddy NangaCenter for Metabolic Imaging in Precision Medicine (CAMIPM), Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-3644-5656
Neil E WilsonCenter for Metabolic Imaging in Precision Medicine (CAMIPM), Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Deepa ThakuriCenter for Metabolic Imaging in Precision Medicine (CAMIPM), Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Paul S JacobsCenter for Metabolic Imaging in Precision Medicine (CAMIPM), Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-3566-4010
Anshuman SwainCenter for Metabolic Imaging in Precision Medicine (CAMIPM), Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Dushyant KumarCenter for Metabolic Imaging in Precision Medicine (CAMIPM), Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-1617-6399
Ravinder ReddyCenter for Metabolic Imaging in Precision Medicine (CAMIPM), Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-4580-2392
University of Pennsylvania · US

Funding

High Spatial and Temporal Resolution MRI Mapping of Oxygen Consumption in HumansP41EB029460 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI Ravinder Reddy · 2021 to 2026
$7.6M
In vivo Mapping of Muscle Specific MetabolismR01AG071725 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Ravinder Reddy · 2022 to 2026
$3.1M
Imaging of glutamatergic system changes in Alzheimer's disease in vivoR01AG063869 · NIA · UNIVERSITY OF PENNSYLVANIA · PI REDDY, RAVINDER · 2020 to 2024
$3.0M
Training in Structural, Physiologic and Functional MRIT32EB020087 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI JAMES C GEE, Chamith Sudesh Rajapakse · 2016 to 2026
$2.1M
CrCEST MRI of Skeletal Muscle MetabolismR56AG062665 · NIA · UNIVERSITY OF PENNSYLVANIA · PI REDDY, RAVINDER · 2019 to 2019
$656k
NIA NIH HHS R01 AG063869NIA NIH HHS R01 AG071725NIA NIH HHS R56 AG062665NIBIB NIH HHS P41 EB029460NIBIB NIH HHS T32 EB020087
6 · The paper itself

Abstract

purposeNuclear Overhauser effect (NOE) is based on dipolar cross-relaxation mechanism that enables the indirect detection of aliphatic protons via the water proton signal. This work focuses on determining the reproducibility of NOE magnetization transfer ratio (NOE

methodsWe optimized the

resultsWe found that a saturation amplitude of 0.72 μT and a length of 3 s provided the highest contrast. We found that the mean NOE

conclusionThis work has demonstrated an excellent reproducibility of both inter- and intrasubject NOE

Indexed as

AlgorithmsBrain NeoplasmsBrainHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingProtonsReproducibility of ResultsProtonsbrainCESTcross-relaxationMTRNOErNOE

Identifiers

PMID36744726
PMCPMC10078808
OpenAlexW4319294845

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.