Evidence map›Paper›PMID 36744630›Full record

ArticleJournal of medical primatology2023

Effects of pair housing on behavior, cortisol, and clinical outcomes during quarantine-like procedures for rhesus macaques (Macaca mulatta).

Martina N Jackson, Melissa A Truelove, Kimberly Williams, Jiandong Chen, Reneé H Moore, Jennifer S Wood, Joyce K Cohen, Bloomsmith Mollie

Open access · hybridAbstract read
In one paragraph

Article in Journal of medical primatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Martina N JacksonAnimal Resources, Emory National Primate Research Center, Atlanta, Georgia, USA.ORCID 0000-0002-3356-0827
Melissa A TrueloveBehavioral Management, Emory National Primate Research Center, Atlanta, Georgia, USA.
Kimberly WilliamsBehavioral Management, Emory National Primate Research Center, Atlanta, Georgia, USA.
Jiandong ChenBiostatistics Collaboration Core, Emory University, Atlanta, Georgia, USA.
Reneé H MooreBiostatistics Collaboration Core, Emory University, Atlanta, Georgia, USA.
Jennifer S WoodAnimal Resources, Emory National Primate Research Center, Atlanta, Georgia, USA.
Joyce K CohenAnimal Resources, Emory National Primate Research Center, Atlanta, Georgia, USA.
Bloomsmith MollieBehavioral Management, Emory National Primate Research Center, Atlanta, Georgia, USA.
Oregon National Primate Research Center · USPublic Risk Management Association · USEmory University · US

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
EXTRAMURAL RES FACIL CONST: REPRODUCTIVE, GROWTH &DVMT, MENOPAUSEC06RR020141 · NCRR · UNIVERSITY OF WISCONSIN MADISON · PI CADWALLADER, MARTIN · 2004 to 2004
$3.6M
EXTRAMURAL REGIONAL FACILITIES CONSTRUCTIONC06RR015459 · NCRR · UNIVERSITY OF WISCONSIN MADISON · PI CADWALLADER, MARTIN · 2000 to 2000
$1.9M
NCRR NIH HHS C06 RR015459NCRR NIH HHS C06 RR020141NIH HHS P51 OD011106NIH HHS P51 OD011132
6 · The paper itself

Abstract

backgroundCompatible pair housing of macaques in research settings increases species-typical behaviors and facilitates beneficial social buffering. It is not yet established whether these benefits are maintained after intrafacility transfer and domestic quarantine, which are two stressors that can lead to behavioral and clinical abnormalities.

methodsWe evaluated 40 adolescent male rhesus macaques who were single- or pair-housed immediately following an intrafacility transfer. We measured behavior, fecal cortisol, body weight, and diarrhea occurrence. Body weight and diarrhea occurrence were also retrospectively analyzed in an additional 120 adolescent rhesus who underwent a similar transfer. RESULTS AND

conclusionsPair-housed macaques exhibited less of some undesirable behaviors (e.g., self-clasping) and experienced less diarrhea than single-housed subjects; however, no significant differences in cortisol levels or alopecia measures were found. The demonstrated beneficial effects of pair housing for rhesus macaques following intrafacility transfer and adjustment suggest pairing upon arrival at a new facility will bolster animal welfare.

Indexed as

HydrocortisoneQuarantineAnimalsBehavior, AnimalHousing, AnimalMacaca mulattaMaleRetrospective StudiesSocial BehaviorHydrocortisoneabnormal behaviordiarrheafecal metabolitesquarantinesocial housingstresstransferwelfare

Identifiers

PMID36744630
PMCPMC10228144
OpenAlexW4319293559

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.