Evidence map›Paper›PMID 36744319›Full record

ArticleCancer discovery2023

Bone Marrow Avatars: Mimicking Hematopoiesis in a Dish.

Marta Derecka, John D Crispino

Open access · bronzeAbstract readEditorialComment
PubMed Publisher
In one paragraph

Article in Cancer discovery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Marta DereckaDepartment of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee.ORCID 0000-0001-6265-9781
John D CrispinoDepartment of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee.ORCID 0000-0002-8182-8306
St. Jude Children's Research Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

summaryFaithful recapitulation of human bone marrow complexity has been a major challenge for the sci-entific community for many years. In this issue of Cancer Discovery, Khan and colleagues present an improved induced pluripotent stem cell differentiation protocol that generates bone marrow organoids re-creating key characteristics of human marrow. See related article by Khan et al., p. 364 (8).

Indexed as

Bone MarrowHematologic NeoplasmsCell DifferentiationHematopoiesisHumansOrganoids

Identifiers

PMID36744319
OpenAlexW4319293792

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.