Evidence map›Paper›PMID 36744035›Full record

SynthesisFrontiers in physiology2023

Mitochondrial dysfunction in cardiovascular disease: Towards exercise regulation of mitochondrial function.

Kunzhe Li, Bingzhi Wan, Sujuan Li, Zhixin Chen, Hao Jia, Yinping Song, Jiamin Zhang, Wenyu Ju, Han Ma, Youhua Wang

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Molecular Research in Cardiovascular Disease, 3rd Edition.International journal of molecular sciences · 2026
    Article
  3. Review
  4. Article
  5. Cardioprotective Role of CalhexCell biochemistry and biophysics · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Kunzhe LiSchool of Physical Education, Institute of Sports and Exercise Biology, Shaanxi Normal University, Xi'an, China.
Bingzhi WanPhysical Education Department, Xidian University, Xi'an, China.
Sujuan LiSchool of Physical Education, Institute of Sports and Exercise Biology, Shaanxi Normal University, Xi'an, China.
Zhixin ChenSchool of Physical Education, Institute of Sports and Exercise Biology, Shaanxi Normal University, Xi'an, China.
Hao JiaSchool of Physical Education, Institute of Sports and Exercise Biology, Shaanxi Normal University, Xi'an, China.
Yinping SongSchool of Physical Education, Institute of Sports and Exercise Biology, Shaanxi Normal University, Xi'an, China.
Jiamin ZhangSchool of Physical Education, Institute of Sports and Exercise Biology, Shaanxi Normal University, Xi'an, China.
Wenyu JuSchool of Physical Education, Institute of Sports and Exercise Biology, Shaanxi Normal University, Xi'an, China.
Han MaSchool of Physical Education, Institute of Sports and Exercise Biology, Shaanxi Normal University, Xi'an, China.
Youhua WangSchool of Physical Education, Institute of Sports and Exercise Biology, Shaanxi Normal University, Xi'an, China.
Shaanxi Normal University · CNXidian University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The morbidity and mortality of cardiovascular diseases are exceedingly high worldwide. Pathological heart remodeling, which is developed as a result of mitochondrial dysfunction, could ultimately drive heart failure. More recent research target exercise modulation of mitochondrial dysfunction to improve heart failure. Therefore, finding practical treatment goals and exercise programs to improve cardiovascular disease is instrumental. Better treatment options are available with the recent development of exercise and drug therapy. This paper summarizes pathological states of abnormal mitochondrial function and intervention strategies for exercise therapy.

Indexed as

cardiovascular diseasesexercisemitochondrial autophagymitochondrial dynamicsmitochondrial energy metabolism

Identifiers

PMID36744035
PMCPMC9892907
OpenAlexW4317402182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.