Evidence map›Paper›PMID 36743912›Full record

ArticleFrontiers in endocrinology2022

Relationship between serum thyroid hormones and their associated metabolites, and gene expression bioindicators in the back skin of

Rikke Poulsen, Shireen H Jackman, Martin Hansen, Caren C Helbing

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 8 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Rikke PoulsenDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Shireen H JackmanDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada.
Martin HansenDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Caren C HelbingDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada.
Aarhus University · DKUniversity of Victoria · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anuran metamorphosis is characterized by profound morphological changes including remodeling of tissues and organs. This transition is initiated by thyroid hormones (THs). However, the current knowledge of changing levels of THs during metamorphosis relies on pooled samples using methods known for high variability with sparse reporting of measured variation. Moreover, establishing a clear linkage between key gene expression bioindicators and TH levels throughout the metamorphic process is needed. Using state-of-the-art ultra-high performance liquid chromatography isotope-dilution tandem mass spectrometry, we targeted 12 THs and metabolites in the serum of

Indexed as

Environmental BiomarkersThyroid HormonesAnimalsAnuraGene ExpressionLarvaRana catesbeianaRanidaeThyroid Hormone Receptors betaEnvironmental BiomarkersThyroid Hormone Receptors betaThyroid Hormonesamphibian metamorphosisbioindicatorsgene expressionRana catesbeiana (Anura)thyroid hormoneuntargeted metabolomicsXenopus comparison

Identifiers

PMID36743912
PMCPMC9889540
OpenAlexW4317396543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.