Evidence map›Paper›PMID 36743906›Full record

ArticleCureus2023

A Case of Paradoxical Cerebral Embolism Due to Pulmonary Arteriovenous Fistula Mimicking Vertebral Artery Dissection With Wallenberg Syndrome.

Masaru Isogai, Tomoaki Suzuki, Shyunichi Kato, Yoshinori Taniguchi, Hitoshi Hasegawa, Makoto Oishi, Yukihiko Fujii

Registry-linked trialOpen access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07680595 (A Prospective, Exploratory, Cohort Clinical Study Comparing the Effects of Oral Statins With or Without Folic Acid on Carotid Plaque Stability.), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07680595 phase1 / phase2recruitingstarted 2026, after this paper: background citation

A Prospective, Exploratory, Cohort Clinical Study Comparing the Effects of Oral Statins With or Without Folic Acid on Carotid Plaque Stability.

Ran2026Enrolled180Registered outcomes5Posted comparisons0ConditionsCarotid Atherosclerotic PlaqueArmsAtorvastatin, Atorvastatin plus folic acid
Open the trial in the graph
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Masaru IsogaiDepartment of Neurosurgery, Nagaoka Chuo General Hospital, Nagaoka, JPN.
Tomoaki SuzukiDepartment of Neurosurgery, Niigata University, Brain Research Institute, Niigata, JPN.
Shyunichi KatoDepartment of Neurosurgery, Nagaoka Chuo General Hospital, Nagaoka, JPN.
Yoshinori TaniguchiDepartment of Neurosurgery, Nagaoka Chuo General Hospital, Nagaoka, JPN.
Hitoshi HasegawaDepartment of Neurosurgery, Niigata University, Brain Research Institute, Niigata, JPN.
Makoto OishiDepartment of Neurosurgery, Niigata University, Brain Research Institute, Niigata, JPN.
Yukihiko FujiiDepartment of Neurosurgery, Niigata University, Brain Research Institute, Niigata, JPN.
Niigata University · JPNagaoka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary arteriovenous fistula (PAVF) leads to paradoxical cerebral embolism, which can be fatal if left untreated. We report a rare case of brainstem infarction with acute severe headache and Wallenberg syndrome caused by a PAVF mimicking vertebral artery (VA) dissection. A 40-year-old man presented with a sudden occipital headache accompanied by right hemisensory disturbance. Magnetic resonance imaging revealed left lateral medullary infarction and poor depiction of the left VA. However, it was clearly recanalized on day six, and there were no findings of VA dissection. Whole-body contrast-enhanced computed tomography (CT) revealed a PAVF in the right lung and a thrombus in the feeding artery. The patient was diagnosed with hereditary hemorrhagic telangiectasia due to recurrent epistaxis and peripheral vasodilation of the tongue. An anticoagulant was administered for preventing further ischemic stroke, and a follow-up CT confirmed the disappearance of the thrombus in three months. Thoracoscopic partial lung resection was performed five months after the onset, and no recurrence of ischemic stroke was observed.

Indexed as

double origin of the posterior inferior cerebellar arteryhereditary hemorrhagic telangiectasiaparadoxical cerebral embolismpulmonary arteriovenous fistulawallenberg syndrome

Identifiers

PMID36743906
PMCPMC9896129
OpenAlexW4318946771

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.