Evidence map›Paper›PMID 36743751›Full record

ArticleJournal of neurosciences in rural practice

Outcomes in pituitary adenoma causing acromegaly following endoscopic endonasal transsphenoidal surgery.

Rajesh Chhabra, Ashwani Kumar, R S Virk, Pinaki Dutta, Chirag Ahuja, Manju Mohanty, Sivashanmugam Dhandapani

Open access · goldAbstract read
In one paragraph

Article in Journal of neurosciences in rural practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rajesh ChhabraDepartment of Neurosurgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Ashwani KumarDepartment of Neurosurgery, Government Medical College and Hospital, Chandigarh, India.
R S VirkDepartment of Otorhinolaryngology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Pinaki DuttaDepartment of Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Chirag AhujaDepartment of Neuroradiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Manju MohantyDepartment of Neurosurgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Sivashanmugam DhandapaniDepartment of Neurosurgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Post Graduate Institute of Medical Education and Research · INGovernment Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The objectives of the study were to study the analysis of outcomes after endoscopic endonasal transsphenoidal surgery (EETSS) in acromegaly in terms of surgical complications, clinical improvement, endocrinological remission, achievement of prognostically critical growth hormone (GH) level, and requirement of additional treatment. Materials and Methods: The study included 28 acromegaly patients, who underwent EETSS. A 2010 consensus criterion was used for defining remission. Assessment of prognostically critical GH level (random value <2.5 ng/ml), the extent of resection and additional treatment, was done at post-operative week (POW) 12. Results: All adenomas were macroadenomas; with a mean volume of 16.34 cm Conclusion: A successful EETSS can reduce adenoma volume to achieve clinical improvement, endocrinologic remission, and prognostically critical GH level with some complications related to surgery. Pre-operative larger volume and higher extension grades affect these outcomes adversely.

Indexed as

AcromegalyEndoscopic endonasal transsphenoidal surgeryPituitary adenoma

Identifiers

PMID36743751
PMCPMC9894003
OpenAlexW4311893468

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.