Evidence map›Paper›PMID 36743742›Full record

ArticleJournal of neurosciences in rural practice

Effectiveness of prophylactic iron supplementation in the reduction of recurrence of febrile seizures in children: A prospective study with comparison with historical controls.

Indar Kumar Sharawat, Prateek Kumar Panda, Vinod Kumar, Aparna Ramachandran, Sanjot Bhardwaj, Vignesh Kaniyappan Murugan, Amit Kumar Pradhan, Rajkali Rajendiran, Nowneet Kumar Bhat

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In one paragraph

Article in Journal of neurosciences in rural practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution.

Indar Kumar SharawatDepartment of Pediatrics, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Prateek Kumar PandaDepartment of Pediatrics, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Vinod KumarDepartment of Pediatrics, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Aparna RamachandranDepartment of Neurology, IQRAA International Hospital and Research Centre, Kozhikode, Kerala, India.
Sanjot BhardwajDepartment of Pediatrics, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Vignesh Kaniyappan MuruganDepartment of Pediatrics, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Amit Kumar PradhanDepartment of Pediatrics, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Rajkali RajendiranDepartment of Pediatrics, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.ORCID https://orcid.org/0000-0003-0731-2480
Nowneet Kumar BhatDepartment of Pediatrics, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
All India Institute of Medical Sciences Rishikesh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The primary objective of the study was to compare the number of patients with febrile seizure recurrence within 1 year of presenting to our institute, among patients who received and didn't receive oral iron supplementation. Materials and Methods: This prospective intervention study with historical controls was conducted to compare the number of patients with febrile seizure recurrence within 1 year, among patients who received and did not receive oral iron supplementation. The intervention group additionally received prophylactic iron supplementation of 20 mg biweekly for 1 year. Results: A total of 53 patients each were enrolled in both the groups, with comparable baseline characteristics. Although there was a trend toward a lower rate of recurrence of febrile seizures in the interventional group, as compared to the control group, it did not reach the point of statistical significance ( Conclusion: Oral serum iron supplementation does not significantly reduce the recurrence rate of febrile seizures in children aged 6-60 months. However, there is a trend toward reduction in the frequency of recurrence of febrile seizures, which is more pronounced in the subset with complex febrile seizures.

Indexed as

Childhood epilepsyFebrile seizuresIron-deficiency anemiaNutritional deficiencyRecurrenceSupplementation

Identifiers

PMID36743742
PMCPMC9893947
OpenAlexW4309463279

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.