Evidence map›Paper›PMID 36743530›Full record

ArticleJAC-antimicrobial resistance2023

Identification and characterization of plasmids carrying the mobile colistin resistance gene

Sriram Kk, Moa S Wranne, Tsegaye Sewunet, Elina Ekedahl, Maarten Coorens, Teerawit Tangkoskul, Visanu Thamlikitkul, Christian G Giske, Fredrik Westerlund

Open access · goldAbstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Sriram KkDepartment of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.ORCID https://orcid.org/0000-0002-4661-242X
Moa S WranneDepartment of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
Tsegaye SewunetDivision of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden.
Elina EkedahlDepartment of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
Maarten CoorensClinical Microbiology, Karolinska University Hospital, Stockholm, Sweden.
Teerawit TangkoskulFaculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Visanu ThamlikitkulFaculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0002-0044-5988
Christian G GiskeDivision of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden.
Fredrik WesterlundDepartment of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.ORCID https://orcid.org/0000-0002-4767-4868
Chalmers University of Technology · SEKarolinska University Hospital · SESiriraj Hospital · THKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Colistin is a last-resort antibiotic, but there has been a rapid increase in colistin resistance, threatening its use in the treatment of infections with carbapenem-resistant Methods: ODM is a single-molecule technique, which we have demonstrated can be used for identifying plasmids harbouring antibiotic resistance genes. We here applied the technique to plasmids isolated from 12 clinical Results: We successfully identified plasmids encoding the Conclusions: Both ODM and the cut-and-stretch assay developed could be very useful in identifying plasmids encoding antibiotic resistance in hospitals and healthcare facilities. The cut-and-stretch assay is particularly useful in low- and middle-income countries, where existing techniques are limited.

Identifiers

PMID36743530
PMCPMC9891347
OpenAlexW4318833853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.