Evidence map›Paper›PMID 36743417›Full record

ArticleFrontiers in cell and developmental biology2023

Clinical phase I/II trial of SVF therapy for cartilage regeneration: A cellular therapy with novel 3D MRI imaging for evaluating chondral defect of knee osteoarthritis.

Bin Ren, Yiqiang Chang, Ruolan Liu, Feng Xiao, Jun Xu, Lingsong Li, Tao Li, Zhao Ruan, Yigui Bao, Junbing Lin and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Stem cell injections for osteoarthritis of the knee.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Comparative outcome analyses of stromal vascular fractionWorld journal of experimental medicine · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Repair, Regeneration, and Replacement, Revisited (Redux).Journal of diabetes science and technology · 2025
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Bin RenDepartment of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, China.
Yiqiang ChangDepartment of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, China.
Ruolan LiuDepartment of Rehabilitation Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
Feng XiaoDepartment of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Jun XuPlastic Surgery, General Hospital of the People's Liberation Army, Beijing, China.
Lingsong LiShanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, China.
Tao LiDepartment of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Zhao RuanDepartment of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Yigui BaoDepartment of Rehabilitation Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
Junbing LinDepartment of Rehabilitation Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
Junying ZhouClinic Laboratory, Zhongnan Hospital of Wuhan University, Wuhan, China.
Weijing LiaoDepartment of Rehabilitation Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
Zhenyu PanDepartment of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, China.
Haibo XuDepartment of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Jun TianDepartment of Rehabilitation Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
Lin CaiDepartment of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, China.
Xin Xiao ZhengDepartment of Plastic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, United States.
Wuhan University · CNZhongnan Hospital of Wuhan University · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

3D MRI imagingcartilage regenerationclinical trialosteoarthritisstromal vascular fraction (SVF)

Identifiers

PMID36743417
PMCPMC9892457
OpenAlexW4317388421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.