Evidence map›Paper›PMID 36743287›Full record

ArticleFrontiers in molecular neuroscience2022

Lipidomic changes of cerebral cortex in aldehyde dehydrogenase-2 knock-in heterozygote mice after chronic alcohol exposure.

Li Xiao, Jin Xiang, Xinyu Liu, Lin Yang, Ying Wei, Shiyong Fang, Jing Li, Yi Ye

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Li XiaoDepartment of Forensic Toxicological Analysis, West China School of Basic Medical Sciences and Forensic Medicine, Sichuan University, Chengdu, Sichuan, China.
Jin XiangClinical Pharmacology Lab, Clinical Trial Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Xinyu LiuWest China School of Basic Medical Sciences and Forensic Medicine, Sichuan University, Chengdu, Sichuan, China.
Lin YangDepartment of Forensic Toxicological Analysis, West China School of Basic Medical Sciences and Forensic Medicine, Sichuan University, Chengdu, Sichuan, China.
Ying WeiCollege of Pharmacy, North Sichuan Medical College, Nanchong, Sichuan, China.
Shiyong FangSchool of Forensic Medicine, Wannan Medical College, Wuhu, China.
Jing LiDepartment of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Bavaria, Germany.
Yi YeDepartment of Forensic Toxicological Analysis, West China School of Basic Medical Sciences and Forensic Medicine, Sichuan University, Chengdu, Sichuan, China.
West China Medical Center of Sichuan University · CNNorth Sichuan Medical University · CNSichuan University · CNUniversity Hospital Regensburg · DEWannan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Alcohol is the main legal drug in the world, and excessive consumption of alcohol seriously damages the morphological structure and function of various organs. The insufficiency of an essential enzyme in ethanol metabolism, aldehyde dehydrogenase-2 ( Methods: In this study, Results and Discussion: Compared with similarly treated wild-type (WT) mice, Highlights: • The cerebral cortex of heterozygous

Indexed as

ALDH2cerebral cortexchronic alcohol exposureknock-inlipidomics

Identifiers

PMID36743287
PMCPMC9893510
OpenAlexW4317425662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.