Evidence map›Paper›PMID 36743151›Full record

ArticleJournal of lasers in medical sciences2022

The Combined Effects of a Methacrylate Powder Dressing (Altrazeal Powder) and Photobiomodulation Therapy on the Healing of a Severe Diabetic Foot Ulcer in a Diabetic Patient: A Case Report.

Roya Derakhshan, Houssein Ahmadi, Mohammad Bayat, Leila Mehboudi, Erfan Pourhashemi, Abdollah Amini, Dorsa Vatandoust, Shahin Aghamiri, Robabeh Asadi, Babak Sabet

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Journal of lasers in medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Roya DerakhshanEndometriosis Research Center, Iran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0001-7425-3412
Houssein AhmadiDepartment of Biology and Anatomical Sciences, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran.ORCID https://orcid.org/0000-0002-6300-4143
Mohammad BayatDepartment of Biology and Anatomical Sciences, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran.ORCID https://orcid.org/0000-0001-5214-4223
Leila MehboudiDepartment of Anesthesia, Faculty of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran.ORCID https://orcid.org/0000-0002-8002-7590
Erfan PourhashemiSchool of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran.ORCID https://orcid.org/0000-0001-7418-5990
Abdollah AminiDepartment of Biology and Anatomical Sciences, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran.ORCID https://orcid.org/0000-0002-9408-3200
Dorsa VatandoustDepartment of Biology and Anatomical Sciences, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran.ORCID https://orcid.org/0000-0002-7456-3215
Shahin AghamiriStudent Research Committee, Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-1083-1409
Robabeh AsadiDepartment of Paramedicine, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-8962-4068
Babak SabetDepartment of Surgery, School of Medicine, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran.ORCID https://orcid.org/0000-0001-6436-9614
Shahid Beheshti University of Medical Sciences · IRIran University of Medical Sciences · IRJahrom University · IRShahroud University of Medical Sciences · IRTehran University of Medical Sciences · IRUniversity of Louisville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Weakened wound healing is a popular, severe complication of patients with diabetes which poses a risk for foot infection and amputation. Researchers have searched for new treatments for treating diabetic foot ulcers (DFUs) in recent years. In this case report, for the first time, we applied photobiomodulation therapy (PBMT) and Altrazeal powder together to treat a severe case of DFU in a 47-year-old woman who was suffering from type 1 diabetes. Along with the progress of combination therapy, we observed that the ulcer area was significantly reduced, and the wound healed within 16 weeks. Furthermore, dermatitis and purulent secretion were treated, and the pain was reduced. This reported case study indicated the beneficial effect of the combination of PBMT and Altrazeal powder for the healing of a severe DFU in a patient with type one diabetes. The combined application of PBMT plus Altrazeal powder demonstrated an additive effect. Further clinical trials in the clinical setting are suggested to validate the results further. Besides, more studies in preclinical models are suggested to find the mechanism of the action of combination therapy.

Indexed as

Altrazeal powderDiabetes mellitusDiabetic foot ulcerPhotobiomodulation therapyWound healing

Identifiers

PMID36743151
PMCPMC9841389
OpenAlexW4318213440

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.