Evidence map›Paper›PMID 36743074›Full record

ArticleACS omega2023

Traceless Staudinger Ligation to Access Stable Aminoacyl- or Peptidyl-Dinucleotide.

Camélia Kitoun, Saidbakhrom Saidjalolov, Delphine Bouquet, Fabiola Djago, Quentin Blancart Remaury, Bruno Sargueil, Pauline Poinot, Mélanie Etheve-Quelquejeu, Laura Iannazzo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Camélia KitounUniversité Paris Cité, CNRS, Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, Paris F-75006, France.
Saidbakhrom SaidjalolovUniversité Paris Cité, CNRS, Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, Paris F-75006, France.
Delphine BouquetUniversité Paris Cité, CNRS, Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, Paris F-75006, France.
Fabiola DjagoInstitut de Chimie des Milieux et Matériaux de Poitiers IC2MP, Université de Poitiers, UMR 7285, Poitiers 86073, France.
Quentin Blancart RemauryInstitut de Chimie des Milieux et Matériaux de Poitiers IC2MP, Université de Poitiers, UMR 7285, Poitiers 86073, France.
Bruno SargueilUniversité Paris Cité, CNRS, UMR 8038/CiTCoM, Paris F-75006, France.
Pauline PoinotInstitut de Chimie des Milieux et Matériaux de Poitiers IC2MP, Université de Poitiers, UMR 7285, Poitiers 86073, France.ORCID https://orcid.org/0000-0002-7927-1887
Mélanie Etheve-QuelquejeuUniversité Paris Cité, CNRS, Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, Paris F-75006, France.ORCID https://orcid.org/0000-0002-4105-3243
Laura IannazzoUniversité Paris Cité, CNRS, Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, Paris F-75006, France.ORCID https://orcid.org/0000-0002-2181-4885
Centre National de la Recherche Scientifique · FRUniversité de Poitiers · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aminoacyl- and peptidyl-tRNA are specific biomolecules involved in many biological processes, from ribosomal protein synthesis to the synthesis of peptidoglycan precursors. Here, we report a post-synthetic approach based on traceless Staudinger ligation for the synthesis of a stable amide bond to access aminoacyl- or peptidyl-di-nucleotide. A series of amino-acid and peptide ester phenyl phosphines were synthetized, and their reactivity was studied on a 2'-N

Identifiers

PMID36743074
PMCPMC9893454
OpenAlexW4316987263

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.