Evidence map›Paper›PMID 36742358›Full record

ReviewFrontiers in human neuroscience2023

Neural basis of dysphagia in stroke: A systematic review and meta-analysis.

Yin Qin, Yuting Tang, Xiaoying Liu, Shuting Qiu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in human neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Observational
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Classifying neurogenic dysphagia as a movement disorder.Brain : a journal of neurology · 2025
    Review
  11. Article
  12. Multimodal Neural Assessment for Predicting Post-Stroke Dysphagia: Identifying Critical Risk Factors Using Combined Indicators.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Impact of rTMS and iTBS on Cerebral Hemodynamics and Swallowing in Unilateral Stroke: Insights from fNIRS.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yin QinDepartment of Rehabilitation Medicine, The 900th Hospital of Joint Logistic Support Force, People's Liberation Army (PLA), Fuzhou, China.
Yuting TangDepartment of Rehabilitation Medicine, The 900th Hospital of Joint Logistic Support Force, People's Liberation Army (PLA), Fuzhou, China.
Xiaoying LiuDepartment of Rehabilitation Medicine, The 900th Hospital of Joint Logistic Support Force, People's Liberation Army (PLA), Fuzhou, China.
Shuting QiuDepartment of Rehabilitation Medicine, The 900th Hospital of Joint Logistic Support Force, People's Liberation Army (PLA), Fuzhou, China.
117th Hospital of People's Liberation Army · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Dysphagia is a major cause of stroke infection and death, and identification of structural and functional brain area changes associated with post-stroke dysphagia (PSD) can help in early screening and clinical intervention. Studies on PSD have reported numerous structural lesions and functional abnormalities in brain regions, and a systematic review is lacking. We aimed to integrate several neuroimaging studies to summarize the empirical evidence of neurological changes leading to PSD. Methods: We conducted a systematic review of studies that used structural neuroimaging and functional neuroimaging approaches to explore structural and functional brain regions associated with swallowing after stroke, with additional evidence using a live activation likelihood estimation (ALE) approach. Results: A total of 35 studies were included, including 20 studies with structural neuroimaging analysis, 14 studies with functional neuroimaging analysis and one study reporting results for both. The overall results suggest that structural lesions and functional abnormalities in the sensorimotor cortex, insula, cerebellum, cingulate gyrus, thalamus, basal ganglia, and associated white matter connections in individuals with stroke may contribute to dysphagia, and the ALE analysis provides additional evidence for structural lesions in the right lentiform nucleus and right thalamus and functional abnormalities in the left thalamus. Conclusion: Our findings suggest that PSD is associated with neurological changes in brain regions such as sensorimotor cortex, insula, cerebellum, cingulate gyrus, thalamus, basal ganglia, and associated white matter connections. Adequate understanding of the mechanisms of neural changes in the post-stroke swallowing network may assist in clinical diagnosis and provide ideas for the development of new interventions in clinical practice.

Indexed as

activation likelihood estimationdysphagiamagnetic resonance imagingmetastroke

Identifiers

PMID36742358
PMCPMC9896523
OpenAlexW4317539132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.