Evidence map›Paper›PMID 36742199›Full record

ReviewFrontiers in cell and developmental biology2022

Cardiac calcium regulation in human induced pluripotent stem cell cardiomyocytes: Implications for disease modeling and maturation.

Patrick Ernst, Philip A Bidwell, Michaela Dora, David D Thomas, Forum Kamdar

Abstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Simultaneous Measurement of Contractile Force and CaSensors (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
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  15. Review
  16. Article
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  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Patrick ErnstCardiovascular Division, University of Minnesota, Minneapolis, MN, United States.
Philip A BidwellCardiovascular Division, University of Minnesota, Minneapolis, MN, United States.
Michaela DoraCollege of Biological Sciences, University of Minnesota, Minneapolis, MN, United States.
David D ThomasDepartment of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN, United States.
Forum KamdarCardiovascular Division, University of Minnesota, Minneapolis, MN, United States.

Funding

Structural Dynamics of Cardiac Muscle Calcium ATPase RegulationR01HL139065 · NHLBI · UNIVERSITY OF MINNESOTA · PI Robyn T Rebbeck, David D Thomas · 2020 to 2026
$5.2M
Training Program in Cardiac InnovationT32HL144472 · NHLBI · UNIVERSITY OF MINNESOTA · PI Peter A Crawford, SAMUEL C DUDLEY · 2019 to 2026
$2.6M
NHLBI NIH HHS R01 HL139065NHLBI NIH HHS T32 HL144472
6 · The paper itself

Abstract

Human induced pluripotent stem cell cardiomyocytes (hiPSC-CMs) are based on ground-breaking technology that has significantly impacted cardiovascular research. They provide a renewable source of human cardiomyocytes for a variety of applications including

Indexed as

calciumcardiomyocytesdisease modelinggenetic cardiovascular diseaseshuman induced pluripotent stem cellsmaturationstem cells

Identifiers

PMID36742199
PMCPMC9889838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.