Evidence map›Paper›PMID 36742058›Full record

ArticleFrontiers in neurology2022

Rapid onset of functional tic-like behaviors among adolescent girls-Minnesota, September-November 2021.

Melanie J Firestone, Stacy Holzbauer, Christine Conelea, Richard Danila, Kirk Smith, Rebecca H Bitsko, Susan M Klammer, Stefan Gingerich, Ruth Lynfield

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. A systematic review to characterize functional tic-like behaviors.Frontiers in child and adolescent psychiatry · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Melanie J FirestoneEpidemic Intelligence Service, Centers for Disease Control and Prevention (CDC), Atlanta, GA, United States.
Stacy HolzbauerMinnesota Department of Health, St. Paul, MN, United States.
Christine ConeleaDepartment of Psychiatry and Behavioral Sciences, University of Minnesota Medical School, Minneapolis, MN, United States.
Richard DanilaMinnesota Department of Health, St. Paul, MN, United States.
Kirk SmithMinnesota Department of Health, St. Paul, MN, United States.
Rebecca H BitskoDivision of Human Development and Disability, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention (CDC), Atlanta, GA, United States.
Susan M KlammerMinnesota Department of Health, St. Paul, MN, United States.
Stefan GingerichMinnesota Department of Health, St. Paul, MN, United States.
Ruth LynfieldMinnesota Department of Health, St. Paul, MN, United States.
Minnesota Department of Health · USCenters for Disease Control and Prevention · USUniversity of Minnesota Medical Center · US

Funding

Care Improving Cognition for ADolescents on the Autism Spectrum (CICADAS)R43MH124542 · NIMH · POSIT SCIENCE CORPORATION · PI LEE, HYUN KYU · 2020 to 2021
$621k
Wiring Adolescents With Social Anxiety via Behavioral Interventions (WASABI): a closed-loop mobile intervention to reduce social anxiety and improve social skillsR43MH121209 · NIMH · POSIT SCIENCE CORPORATION · PI BIAGIANTI, BRUNO · 2019 to 2019
$244k
NIMH NIH HHS R43 MH121209NIMH NIH HHS R43 MH124542
6 · The paper itself

Abstract

Background: On October 15, 2021, the Minnesota Department of Health began investigating a school cluster of students experiencing tic-like behaviors thought to be related to recent COVID-19. The objective of this report is to describe the investigation, key findings, and public health recommendations. Methods: Affected students and proxies were interviewed with a standardized questionnaire including validated depression and anxiety screens. Results: Eight students had tic-like behaviors lasting >24 h after initial report with onset during September 26-October 30, 2021. All eight students were females aged 15-17 years. All students either had a history of depression or anxiety or scored as having more than minimal anxiety or depression on validated screens. Four students previously had confirmed COVID-19: the interval between prior COVID-19 and tic symptom onset varied from more than a year prior to tic symptom onset to at the time of tic symptom onset. Conclusion: The onset of tic-like behaviors at one school in Minnesota appeared to be related more to underlying mental health conditions than recent COVID-19. These findings highlight the need to better understand functional tic-like behaviors and adolescent mental health.

Indexed as

adolescent girlsfunctional neurologic disordersmental healthtic disordertics and Tourette Syndrome

Identifiers

PMID36742058
PMCPMC9892901
OpenAlexW4317401822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.