Evidence map›Paper›PMID 36742051›Full record

ReviewFrontiers in neurology2022

Modulatory effects of mesenchymal stem cells on microglia in ischemic stroke.

Lei Hao, Yongtao Yang, Xiaoli Xu, Xiuming Guo, Qunling Zhan

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lei HaoDepartment of Neurology, The First Branch of The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yongtao YangDepartment of Neurology, The Fifth People's Hospital of Chongqing, Chongqing, China.
Xiaoli XuDepartment of Neurology, The Fifth People's Hospital of Chongqing, Chongqing, China.
Xiuming GuoDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Qunling ZhanDepartment of Neurology, The Fifth People's Hospital of Chongqing, Chongqing, China.
First People's Hospital of Chongqing · CNChongqing Medical University · CNFirst Affiliated Hospital of Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemic stroke accounts for 70-80% of all stroke cases. Immunity plays an important role in the pathophysiology of ischemic stroke. Microglia are the first line of defense in the central nervous system. Microglial functions are largely dependent on their pro-inflammatory (M1-like) or anti-inflammatory (M2-like) phenotype. Modulating neuroinflammation

Indexed as

cell polarizationextracellular vesiclesischemic strokemesenchymal stem cellmicroglia

Identifiers

PMID36742051
PMCPMC9889551
OpenAlexW4317397636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.