Evidence map›Paper›PMID 36741841›Full record

ArticleFrontiers in cardiovascular medicine2022

Electrical, structural, and autonomic atrial remodeling underlies atrial fibrillation in inflammatory atrial cardiomyopathy.

Yoshiko Murakata, Fumi Yamagami, Nobuyuki Murakoshi, DongZhu Xu, Zhonghu Song, Siqi Li, Yuta Okabe, Kazuhiro Aonuma, ZiXun Yuan, Haruka Mori and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. [Integrating Bioinformatics and Machine Learning Algorithms to Screen Inflammatory Biomarkers for Atrial Fibrillation and Experimental Validation].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Article
  2. Article
  3. Immune Regulation in Atrial Cardiomyopathy.Reviews in cardiovascular medicine · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Atrial cardiomyocytes contribute to the inflammatory status associated with atrial fibrillation in right heart disease.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  9. Fine tuning contractility: atrial sarcomere function in health and disease.American journal of physiology. Heart and circulatory physiology · 2024
    Review
  10. Review
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  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Yoshiko MurakataDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Fumi YamagamiDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Nobuyuki MurakoshiDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
DongZhu XuDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Zhonghu SongDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Siqi LiDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Yuta OkabeDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Kazuhiro AonumaDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
ZiXun YuanDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Haruka MoriDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Kazutaka AonumaDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Kazuko TajiriDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Masaki IedaDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
University of Tsukuba · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is growing evidence indicating a close relationship between inflammation and atrial fibrillation (AF). Although underlying inflammatory atrial cardiomyopathy may contribute to the development of AF, the arrhythmogenic remodeling caused by atrial inflammation has not been elucidated in detail. Herein, we examined electrical, structural, and autonomic changes in the atria in a mouse model of autoimmune myocarditis. Methods: BALB/c mice were immunized with cardiac myosin peptide (MyHC-α Results: The mice immunized with MyHC-α Conclusion: Inflammatory atrial cardiomyopathy promotes susceptibility to AF via arrhythmogenic electrical, structural, and autonomic remodeling of the atria.

Indexed as

EAMexperimental autoimmune myocarditisinflammationmyocarditisneurotrophinsympathetic nerve

Identifiers

PMID36741841
PMCPMC9892626
OpenAlexW4319293580

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.