Evidence map›Paper›PMID 36741514›Full record

ReviewChemical science2023

Metal complexes for catalytic and photocatalytic reactions in living cells and organisms.

Hugo Madec, Francisca Figueiredo, Kevin Cariou, Sylvain Roland, Matthieu Sollogoub, Gilles Gasser

Open access · diamondAbstract readReview
In one paragraph

Review in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
8.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 91 citations in OpenAlex.

  1. Review
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  12. Selective Iridium-Catalyzed Reductive Amination Inside Living Cells.Journal of the American Chemical Society · 2025
    Article
  13. Article
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  15. Exploring New Bioorthogonal Catalysts: Scaffold Diversity in Catalysis for Chemical Biology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hugo MadecSorbonne Université, CNRS, Institut Parisien de Chimie Moléculaire Paris France sylvain.roland@sorbonne-universite.fr http://www.ipcm.fr/-Glycochimie-Organique.
Francisca FigueiredoChimie ParisTech, PSL Université, CNRS, Institute of Chemistry for Life and Health Sciences Paris 75005 France kevin.cariou@chimieparistech.psl.eu gilles.gasser@chimieparistech.psl.eu http://www.gassergroup.com.
Kevin CariouChimie ParisTech, PSL Université, CNRS, Institute of Chemistry for Life and Health Sciences Paris 75005 France kevin.cariou@chimieparistech.psl.eu gilles.gasser@chimieparistech.psl.eu http://www.gassergroup.com.
Sylvain RolandSorbonne Université, CNRS, Institut Parisien de Chimie Moléculaire Paris France sylvain.roland@sorbonne-universite.fr http://www.ipcm.fr/-Glycochimie-Organique.
Matthieu SollogoubSorbonne Université, CNRS, Institut Parisien de Chimie Moléculaire Paris France sylvain.roland@sorbonne-universite.fr http://www.ipcm.fr/-Glycochimie-Organique.ORCID https://orcid.org/0000-0003-0500-5946
Gilles GasserChimie ParisTech, PSL Université, CNRS, Institute of Chemistry for Life and Health Sciences Paris 75005 France kevin.cariou@chimieparistech.psl.eu gilles.gasser@chimieparistech.psl.eu http://www.gassergroup.com.ORCID https://orcid.org/0000-0002-4244-5097
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of organometallic catalysis has greatly expanded the synthetic chemist toolbox compared to only exploiting "classical" organic chemistry. Although more widely used in organic solvents, metal-based catalysts have also emerged as efficient tools for developing organic transformations in water, thus paving the way for further development of bio-compatible reactions. However, performing metal-catalysed reactions within living cells or organisms induces additional constraints to the design of reactions and catalysts. In particular, metal complexes must exhibit good efficiency in complex aqueous media at low concentrations, good cell specificity, good cellular uptake and low toxicity. In this review, we focus on the presentation of discrete metal complexes that catalyse or photocatalyse reactions within living cells or living organisms. We describe the different reaction designs that have proved to be successful under these conditions, which involve very few metals (Ir, Pd, Ru, Pt, Cu, Au, and Fe) and range from

Identifiers

PMID36741514
PMCPMC9848159
OpenAlexW4310897253

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.