Evidence map›Paper›PMID 36741418›Full record

ReviewFrontiers in immunology2022

The role of major immune cells in myocardial infarction.

Qiang Feng, Qirong Li, Hengzong Zhou, Liqun Sun, Chao Lin, Ye Jin, Dongxu Wang, Gongliang Guo

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

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  17. The Role of Stem Cells in the Treatment of Cardiovascular Diseases.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Qiang FengDepartment of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, China.
Qirong LiLaboratory Animal Center, College of Animal Science, Jilin University, Changchun, China.
Hengzong ZhouLaboratory Animal Center, College of Animal Science, Jilin University, Changchun, China.
Liqun SunDepartment of Pathogenobiology, Jilin University Mycology Research Center, College of Basic Medical Sciences, Jilin University, Changchun, China.
Chao LinSchool of Grain Science and Technology, Jilin Business and Technology College, Changchun, China.
Ye JinSchool of Pharmacy, Changchun University of Chinese Medicine, Changchun, China.
Dongxu WangLaboratory Animal Center, College of Animal Science, Jilin University, Changchun, China.
Gongliang GuoDepartment of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, China.
Jilin University · CNUnion Hospital · CNChangchun University of Chinese Medicine · CNJilin Province Science and Technology Department · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial infarction (MI) is a cardiovascular disease (CVD) with high morbidity and mortality worldwide, often leading to adverse cardiac remodeling and heart failure, which is a serious threat to human life and health. The immune system makes an important contribution to the maintenance of normal cardiac function. In the disease process of MI, necrotic cardiomyocytes release signals that activate nonspecific immunity and trigger the action of specific immunity. Complex immune cells play an important role in all stages of MI progression by removing necrotic cardiomyocytes and tissue and promoting the healing of damaged tissue cells. With the development of biomaterials, cardiac patches have become an emerging method of repairing MI, and the development of engineered cardiac patches through the construction of multiple animal models of MI can help treat MI. This review introduces immune cells involved in the development of MI, summarizes the commonly used animal models of MI and the newly developed cardiac patch, so as to provide scientific reference for the accurate diagnosis and effective treatment of MI.

Indexed as

Heart FailureMyocardial InfarctionAnimalsHumansImmunity, InnateMyocytes, Cardiacanimal modelheart patchimmune cellsmyocardial infarctionnon-specific immunityspecific immunity

Identifiers

PMID36741418
PMCPMC9892933
OpenAlexW4317402204

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.