Evidence map›Paper›PMID 36741361›Full record

ArticleFrontiers in immunology2022

Exposure to solar ultraviolet radiation establishes a novel immune suppressive lipidome in skin-draining lymph nodes.

Benita C Y Tse, Angela L Ferguson, Yen Chin Koay, Georges E Grau, Anthony S Don, Scott N Byrne

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Benita C Y TseThe University of Sydney, School of Medical Sciences, Faculty of Medicine and Health, Sydney, NSW, Australia.
Angela L FergusonThe University of Sydney, School of Medical Sciences, Faculty of Medicine and Health, Sydney, NSW, Australia.
Yen Chin KoayThe University of Sydney, School of Medical Sciences, Faculty of Medicine and Health, Sydney, NSW, Australia.
Georges E GrauThe University of Sydney, School of Medical Sciences, Faculty of Medicine and Health, Sydney, NSW, Australia.
Anthony S DonThe University of Sydney, School of Medical Sciences, Faculty of Medicine and Health, Sydney, NSW, Australia.
Scott N ByrneThe University of Sydney, School of Medical Sciences, Faculty of Medicine and Health, Sydney, NSW, Australia.
University of Sydney · AUThe Heart Research Institute · AUWestmead Institute for Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability of ultraviolet radiation to suppress the immune system is thought to be central to both its beneficial (protection from autoimmunity) and detrimental (carcinogenic) effects. Previous work revealed a key role for lipids particularly platelet-activating factor and sphingosine-1-phosphate in mediating UV-induced immune suppression. We therefore hypothesized that there may be other UV-induced lipids that have immune regulatory roles. To assess this, mice were exposed to an immune suppressive dose of solar-simulated UV (8 J/cm

Indexed as

LipidomicsUltraviolet RaysAnimalsLymph NodesMicePlatelet Activating FactorSkinPlatelet Activating Factorextracellular vesiclesimmune regulationimmune suppressionlipidsmass spectrometryultraviolet radiation

Identifiers

PMID36741361
PMCPMC9895826
OpenAlexW4319294168

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.