ArticleFrontiers in neurology2023
Serum uric acid to serum creatinine ratio predicts neurological deterioration in branch atheromatous disease.
Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 11 citations in OpenAlex.
- Efficacy and Safety of Intravenous Thrombolysis with Tenecteplase in Patients with Wake-Up Branch Atheromatous Disease.Translational stroke research · 2026Article
- Efficacy and Safety of Tenecteplase in the Treatment of Acute Branch Atheromatous Disease: A Retrospective Multicenter Case-Control Study.Neurology and therapy · 2025Article
- The association between kidney function-standardized serum uric acid levels and stroke risk: insights from the National Health and Nutrition Examination Survey.Frontiers in aging neuroscience · 2025Article
- Early wide systolic pressure excursion is associated with clinical outcomes in acute branch atheromatous disease.Frontiers in neurology · 2025Article
- Relation between uric acid and stroke in aortic dissection.Journal of thoracic disease · 2024Article
- Association of serum uric acid to serum creatinine ratio with 1-year stroke outcomes in patients with acute ischemic stroke: A multicenter observational cohort study.European journal of neurology · 2024Observational
- Relative score of early neurological deterioration in perforator artery infarction: a retrospective study.BMC neurology · 2024Article
- Association between the serum uric acid/serum creatinine ratio and cognitive function in older adults: NHANES in the United States.Scientific reports · 2024Article
- Lower serum uric acid to serum creatinine ratio as a predictor of poor functional outcome after mechanical thrombectomy in acute ischaemic stroke.European journal of neurology · 2024Article
- A machine learning-based predictive model for predicting early neurological deterioration in lenticulostriate atheromatous disease-related infarction.Frontiers in neuroscience · 2024Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and objective: Branch atheromatous disease (BAD) makes patients prone to early neurological deterioration (END), resulting in poor prognosis. The aim of this study was to investigate the association between SUA/SCr and END in BAD stroke patients. Methods: We conducted a retrospective study that included 241 patients with BAD-stroke within 48 h of symptom onset. We divided the patients into the END group and the no END group. END was defined as an NIHSS score increase of more than 2 points within 1 week. SUA/SCr was calculated by the concentration of serum uric acid and creatine (serum uric acid/serum creatine) on admission. Univariate and multivariate analyses were used to identify independent predictors of END in BAD-stroke patients. Results: END was observed in 24.1% (58/241) of the patients in our study. Multiple logistic regression analyses showed that SUA/SCr (aOR, 0.716; 95% CI, 0.538-0.952; Conclusion: SUA/SCr was negatively associated with the risk of END in BAD stroke patients.
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