ArticleBrain & NeuroRehabilitation2021
Effects of Cognitive-Physical Dual-Task Training on Executive Function and Activity in the Prefrontal Cortex of Older Adults with Mild Cognitive Impairment.
Article in Brain & NeuroRehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07005271 (Investigation of the Effects of Virtual Reality-Based Hand Exercises on Cognitive Function and Hand Dexterity in Older Adults With Mild Cognitive Impairment.), which is not on this map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigation of the Effects of Virtual Reality-Based Hand Exercises on Cognitive Function and Hand Dexterity in Older Adults With Mild Cognitive Impairment.
Who cites it
20 citing papers in PubMed, 29 citations in OpenAlex.
- Theta tACS Over the Medial Frontal Cortex Modulates Executive Function in Parkinson's Disease: A Randomized, Sham-Controlled Study.CNS neuroscience & therapeutics · 2026Trial
- Effects of Electronic Sports on Community-Dwelling Older Adults With Mild Cognitive Impairment: A Randomized Controlled Study.Geriatrics & gerontology international · 2026Trial
- Enhancing cognitive and physical performance in older adults through wearable sensor-based interactive cognitive-motor training: a randomized clinical trial.Scientific reports · 2025Trial
- The Effect of Aerobic or Strength Training in Elderly with Cognitive Decline: The Fit4Alz Project.Journal of sports science & medicine · 2025Trial
- Trial
- Effect of Variable Priority Cognitive-Motor Dual-Task Training on Cognitive and Physical Function in Older Adults: A Systematic Review.Brain sciences · 2026Review
- Can aerobic exercise really improve factors related to decision-making capacity in aging? What has been measured, what has been assumed, and what needs to change.Frontiers in sports and active living · 2026Review
- Effectiveness of Combined Cognitive Stimulation and Physical Activity Interventions on Activities of Daily Living, Cognitive Function, and Physical Function in Older People with Mild Cognitive Impairment: A Systematic Review with Meta-Analysis.Journal of clinical medicine · 2025Review
- Dual Task Training Interventions and Mobility-Based Outcomes in Children with Cerebral Palsy: A Scoping Review.Physical & occupational therapy in pediatrics · 2025Article
- Neocortical cholinergic pathology after neonatal brain injury is increased by Alzheimer's disease-related genes in mice.Neurobiology of disease · 2024Article
- Effects of computerized cognitive training on biomarker responses in older adults with mild cognitive impairment: A scoping review.Health science reports · 2024Article
- Feasibility of Virtual Shopping Budget-Management Training on Executive Functions in Healthy Young Adults: A Pilot Study.Brain sciences · 2023Article
- Effects of Personalized Cognitive Training Using Mental Workload Monitoring on Executive Function in Older Adults With Mild Cognitive Impairment.Brain & NeuroRehabilitation · 2023Article
- Does Cognitive-Physical Dual-Task Training Have Better Clinical Outcomes than Cognitive Single-Task Training Does? A Single-Blind, Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2023Article
- Response to Letter to the Editor: Effects of Cognitive-Physical Dual-Task Training on Executive Function and Activity in the Prefrontal Cortex of Older Adults With Mild Cognitive Impairment.Brain & NeuroRehabilitation · 2023Article
- Letter to the Editor: Effects of Cognitive-Physical Dual-Task Training on Executive Function and Activity in the Prefrontal Cortex of Older Adults with Mild Cognitive Impairment.Brain & NeuroRehabilitation · 2023Article
- Engineering Virtuous health habits using Emotion and Neurocognition: Flexibility for Lifestyle Optimization and Weight management (EVEN FLOW).Frontiers in aging neuroscience · 2023Review
- Effects of Personalized Cognitive Training with the Machine Learning Algorithm on Neural Efficiency in Healthy Younger Adults.International journal of environmental research and public health · 2022Article
- Comparison of Dual Task Training Versus Aerobics Training in Improving Cognition in Healthy Elderly Population.Cureus · 2022Article
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1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Effects of cognitive-physical dual-task training on prefrontal cortex (PFC)-dependent function remain unclear. This study investigated the effects of dual-task training on executive function and activity in the PFC of older adults with mild cognitive impairment (MCI). Thirty-six older adults with MCI randomly assigned to the experimental group (EG) performing cognitive-physical dual-task training requiring for simultaneous cognitive tasks and physical exercise (n = 18) or the control group (CG) receiving sing-cognitive training using the computerized cognitive training program focusing on executive function (n = 18) for 16 sessions lasting 40 minutes a session. For the primary outcomes, the Trail Making Test Part B (TMT-B) was used, and for the secondary outcome, activity in the PFC using functional near infrared spectroscopy and the Korean version of instrumental activities of daily living (K-IADL) were evaluated at pre-and post-intervention. After the intervention, the EG achieved a significantly higher improvement in the TMT-B and decreased activity in the PFC during TMT-B testing than the CG. However, there were no significant differences in the K-IADL in both groups. These findings indicate that dual-task training is more effective in improving executive process and decreasing activity in the PFC during cognitive testing than single-cognitive training with limitations of its transfer effect to daily life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.