ArticleRSC advances2023
Novel N-doped carbon dots derived from citric acid and urea: fluorescent sensing for determination of metronidazole and cytotoxicity studies.
Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 90 citations in OpenAlex.
- Tuning carbon quantum dot optics through nitrogen surface chemistry.RSC advances · 2026Article
- Surface engineered nitrogen doped carbon quantum dots for mechanistic understanding and advanced biosensing of antibiotic contaminants: a review.RSC advances · 2026Review
- "Synergistic Effect of CQDs on the Spectroscopic Behaviour and Bioactivity of Azo Dyes: Bio-imaging Applications".Journal of fluorescence · 2026Article
- Nitrogen-Doped Carbon Dot/TiOBiomolecules · 2026Article
- Carbon Dots in Nanomedicine: Advanced Fabrication, Biomedical Applications, and Future Clinical Perspectives.Pharmaceutics · 2026Review
- Cerium-doped carbon dots for multifunctional biomedical applications: enhanced heavy metal sensing, antioxidant-driven wound healing, and RAFT polymer-mediated improved gene complexation capability.Mikrochimica acta · 2026Article
- Design, Synthesis, and Characterization ofACS omega · 2026Article
- Enhanced biosensing of diabetes biomarkers by using rationally engineered carbon dots.RSC advances · 2026Review
- Stable nitrogen-doped carbon quantum dots with pH-controlled fluorescence response for FeScientific reports · 2026Article
- Theranostic Rare-Earth-Doped Carbon Dots: An Effective Nanocarrier For Methotrexate Delivery in Colon Cancer.ACS omega · 2026Article
- Synthesis of carbon dot-mediated gold nanostructures: experimental and quantum chemical insights into turn-on fluorescence sensing ofBeilstein journal of nanotechnology · 2026Article
- Microwave-Assisted Synthesis of Nitrogen-Doped Carbon Dots for Sensitive Fluorescence-Based Urea Detection in Soil.Journal of fluorescence · 2025Article
- The Dose-Dependent Effect of Carbon Quantum Dots as a Photosynthesis Enhancer on Soybean Plant Growth.Nanomaterials (Basel, Switzerland) · 2025Article
- Carbon dot based molecularly imprinted polymer for selective fluorometric determination of tetracycline and metronidazole in pharmaceuticals and human plasma.Scientific reports · 2025Article
- N‑Doped Carbon Dot-Based Nanoconjugates with Simultaneous Generation of Nitric Oxide and Singlet Oxygen for Phototherapeutic Applications.ACS applied nano materials · 2025Article
- Cost-Effective Nanosensor Solutions for Ultra-Sensitive Detection of Metronidazole.Analytical science advances · 2025Review
- Going Above and Beyond: Achieving High Contrast and Higher Offset through Carbon Dot-Based diaCEST MRI Contrast Agent.Chemical & biomedical imaging · 2025Article
- A simple UiO-66-NHADMET & DMPK · 2025Article
- Green synthesis of fluorescent N-doped carbon quantum dots from castor seeds and their applications in cell imaging and pH sensing.Scientific reports · 2024Article
- N-doped carbon quantum dots for the selective detection of OClRSC advances · 2024Article
Corrections and comments
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Authors and funding
10 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blue emitting nitrogen-doped carbon dots were synthesized using citric acid and urea through the hydrothermal method, and the fluorescence quantum yield was 35.08%. We discovered that N-CDs featured excellent robust fluorescence stability and chemical resistance. For metronidazole detection, our N-CDs exhibited quick response time, high selectivity and sensitivity, and low cytotoxicity. Specifically, our N-CDs could detect metronidazole in the linear range of 0-179 μM, and the LOD was 0.25 μM. Furthermore, metronidazole efficaciously quenches the fluorescence of N-CDs, possibly owing to the inner filter effect. Lastly, we have employed our N-CDs to detect metronidazole in commercial metronidazole tablets with high accuracy. Overall, the newly prepared fluorescence sensor, N-CDs, demonstrated a huge potential to detect metronidazole in a simple, efficient, sensitive, and rapid manner.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.