Evidence map›Paper›PMID 36741140›Full record

ArticleRSC advances2023

Synthesis of 2-iminothiazolidin-4-ones

Mingming Zhao, Yiming Guo, Qi Wang, Lanqi Liu, Shujie Zhang, Wei Guo, Lin-Ping Wu, Fayang G Qiu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mingming ZhaoGuangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences Guangzhou 510530 P. R. China wu_linping@gibh.ac.cn qiu_fayang@gibh.ac.cn.
Yiming GuoGuangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences Guangzhou 510530 P. R. China wu_linping@gibh.ac.cn qiu_fayang@gibh.ac.cn.
Qi WangGuangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences Guangzhou 510530 P. R. China wu_linping@gibh.ac.cn qiu_fayang@gibh.ac.cn.
Lanqi LiuGuangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences Guangzhou 510530 P. R. China wu_linping@gibh.ac.cn qiu_fayang@gibh.ac.cn.
Shujie ZhangGuangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences Guangzhou 510530 P. R. China wu_linping@gibh.ac.cn qiu_fayang@gibh.ac.cn.
Wei GuoKey Laboratory of Organo-Pharmaceutical Chemistry of Jiangxi Province, Gannan Normal University Ganzhou 341000 P. R. China guoweigw@126.com.ORCID https://orcid.org/0000-0002-4456-3927
Lin-Ping WuGuangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences Guangzhou 510530 P. R. China wu_linping@gibh.ac.cn qiu_fayang@gibh.ac.cn.ORCID https://orcid.org/0000-0001-7579-2987
Fayang G QiuGuangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences Guangzhou 510530 P. R. China wu_linping@gibh.ac.cn qiu_fayang@gibh.ac.cn.ORCID https://orcid.org/0000-0002-0850-468X
Chinese Academy of Sciences · CNGannan Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper, an efficient synthesis of 2-iminothiazolidin-4-ones through a copper-catalyzed tandem annulation reaction of alkyl amines, isothiocyanates and diazo acetates is presented. Notable advantages of this [2 + 1 + 2] cyclization methodology include readily accessible starting materials, simple operation, mild reaction conditions, high yields, step-economy and diverse functional group tolerance. In addition, the reaction is applicable to the gram scale synthesis and the preparation of bioactive molecules.

Identifiers

PMID36741140
PMCPMC9834997
OpenAlexW4315699909

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.