Evidence map›Paper›PMID 36740773›Full record

ArticleThe Journal of clinical endocrinology and metabolism2023

Aldosterone Synthase Inhibitors and the Treatment of Essential Hypertension.

Celso E Gomez-Sanchez, Elise P Gomez-Sanchez

Abstract read
In one paragraph

Article in The Journal of clinical endocrinology and metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Aldosterone synthase inhibitors: a new option for antihypertensive, cardio-renal protection.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Celso E Gomez-SanchezG. V. (Sonny) Montgomery VA Medical Center, University of Mississippi Medical Center, Jackson, MS 39216, USA.ORCID 0000-0002-9882-2082
Elise P Gomez-SanchezDepartment of Pharmacology, University of Mississippi Medical Center, Jackson, MS 39216, USA.ORCID 0000-0002-4432-4950

Funding

Tracking and Evaluation CoreU54GM115428 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI MASON, SARAH · 2016 to 2025
$38.2M
Adrenal cell ATP1A1 mutations and mechanisms of aldosterone biosynthesisR01HL144847 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI GOMEZ-SANCHEZ, CELSO ENRIQUE · 2019 to 2022
$1.3M
NHLBI NIH HHS R01 HL144847NIGMS NIH HHS U54 GM115428
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HyperaldosteronismHypertensionAldosteroneCytochrome P-450 CYP11B2Essential HypertensionHumansMineralocorticoid Receptor AntagonistsReninAldosteroneCytochrome P-450 CYP11B2Mineralocorticoid Receptor AntagonistsReninaldosterone synthase inhibitorsBaxdrostatmineralocorticoid receptor antagonistsPathway-2primary aldosteronismtreatment-resistant hypertension

Identifiers

PMID36740773
PMCPMC10348457

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.