Evidence map›Paper›PMID 36740694›Full record

ArticleBMC geriatrics2023

Risk factors for self-reported medication adherence in community-dwelling older patients with multimorbidity and polypharmacy: a multicenter cross-sectional study.

Jiaming Liu, Yongpei Yu, Suying Yan, Yan Zeng, Su Su, Tiantian He, Zimin Wang, Qian Ding, Ruixue Zhang, Wenchao Li and 3 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC geriatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Jiaming Liu *Department of Pharmacy, Xuanwu Hospital, Capital Medical University, Beijing, China.
Yongpei Yu *Department of Biostatistics, Peking University Clinical Research Institution, Beijing, China.
Suying YanDepartment of Pharmacy, Xuanwu Hospital, Capital Medical University, Beijing, China.
Yan ZengDepartment of Pharmacy, Xuanwu Hospital, Capital Medical University, Beijing, China.
Su SuDepartment of Pharmacy, Xuanwu Hospital, Capital Medical University, Beijing, China.
Tiantian HeDepartment of Biostatistics, Peking University Clinical Research Institution, Beijing, China.
Zimin WangDepartment of Pharmacy, Xuanwu Hospital, Capital Medical University, Beijing, China.
Qian DingDepartment of Pharmacy, Xuanwu Hospital, Capital Medical University, Beijing, China.
Ruixue ZhangDepartment of Pharmacy, Xuanwu Hospital, Capital Medical University, Beijing, China.
Wenchao LiDepartment of Pharmacy, Xuanwu Hospital, Capital Medical University, Beijing, China.
Xin WangDepartment of Medical Affairs, Xuanwu Hospital, Capital Medical University, Beijing, China.
Lan ZhangDepartment of Pharmacy, Xuanwu Hospital, Capital Medical University, Beijing, China.
Xiaolin YueEthics Committee, Xuanwu Hospital, Capital Medical University, Beijing, China. yxl@xwhosp.org.
Capital Medical University · CNPeking University · CN

Funding

Beijing Municipal Health Commission 11000022T000000444688Beijing Municipal Science and Technology Commission D181100000218002
6 · The paper itself

Abstract

backgroundMedication nonadherence is a significant public health problem as it contributes to poor clinical outcomes and increased healthcare costs. Older patients with multimorbidity and polypharmacy often have low medication adherence. These patients also have a high prevalence of potentially inappropriate medication (PIM) use.

aimTo explore risk factors related to medication nonadherence in older patients with multimorbidity and polypharmacy and examine the association between medication nonadherence and PIM use.

methodA multicenter cross-sectional study was conducted from May to December 2019 in 16 tertiary hospitals from 12 provinces and cities in China. Data were collected from outpatients 65 years or older with multimorbidity and polypharmacy. The PIMs were evaluated using the 2019 Beers Criteria. Self-reported medication adherence was assessed using the Visual Analog Scale (VAS).

resultsA total of 773 outpatients were recruited. The prevalence of medication nonadherence was 31.8%. In the univariate analysis, nonadherence was significantly associated with sex, cognitive impairment, stroke, visiting the same physicians, self-administration of medication, the percentage of drug costs ≥ 10% of the medical expenses, and PIMs for the alimentary tract and metabolism. In the multivariate analysis, the results almost paralleled those of the univariate associations. Notably, the use of PIM was significantly associated with medication adherence.

conclusionSeveral factors that influence medication adherence were identified. Targeted interventions can be implemented to improve medication adherence, such as encouraging self-administering medications and reducing medication expenses.

Indexed as

MultimorbidityPolypharmacyAgedCross-Sectional StudiesHumansInappropriate PrescribingIndependent LivingMedication AdherencePotentially Inappropriate Medication ListRisk FactorsSelf ReportMedication adherenceMultimorbidityOlder adultsPolypharmacyPotentially inappropriate medication

Identifiers

PMID36740694
PMCPMC9900971
OpenAlexW4319293961

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.