Evidence map›Paper›PMID 36740196›Full record

SynthesisSurvey of ophthalmology

Efficacy of Ahmed and Baerveldt glaucoma drainage device implantation in the pediatric population: A systematic review and meta-analysis.

Jeannette Y Stallworth, Kieran S O'Brien, Ying Han, Julius T Oatts

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Survey of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jeannette Y StallworthDepartment of Ophthalmology, University of California, San Francisco, San Francisco, CA, USA.
Kieran S O'BrienDepartment of Ophthalmology, University of California, San Francisco, San Francisco, CA, USA; San Francisco, Francis I. Proctor Foundation, University of California, San Francisco, CA, USA.
Ying HanDepartment of Ophthalmology, University of California, San Francisco, San Francisco, CA, USA.
Julius T OattsDepartment of Ophthalmology, University of California, San Francisco, San Francisco, CA, USA. Electronic address: julius.oatts@ucsf.edu.
University of California, San Francisco · US

Funding

Rapid-Prototyping and Design CoreP30EY002162 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LAMBA, DEEPAK ASHOK · 1985 to 2024
$16.8M
Glaucoma Drainage Device and Endothelial Cell Density Loss Compare (DECLARE) TrialUG1EY033703 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Ying Han, Jennifer Rose-Nussbaumer · 2023 to 2026
$4.4M
UCSF-Proctor Clinician Vision Scholars K12 ProgramK12EY031372 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI THOMAS M LIETMAN, Yvonne Ou · 2020 to 2026
$3.9M
NEI NIH HHS K12 EY031372NEI NIH HHS P30 EY002162NEI NIH HHS UG1 EY033703
6 · The paper itself

Abstract

Glaucoma drainage devices (GDD) are increasingly utilized in the management of childhood glaucoma. This systematic review and meta-analysis assesses the efficacy of first-time Ahmed or Baerveldt implantation in children. PubMed, Embase, and Cochrane Library were searched for relevant English-language, peer-reviewed literature. Postoperative outcomes were pooled using random effects regression models with restricted maximum likelihood estimation. Thirty-two studies (1,221 eyes, 885 children) were included. Mean ± standard deviation preoperative IOP was 31.8 ± 3.4 mm Hg. Pooled mean IOP at 12 and 24 months postoperatively were 16.5 mm Hg (95% CI, 15.5-17.6) and 17.6 mm Hg (95% CI, 16.4-18.7), respectively. Pooled proportions of success were 0.87 (95% CI, 0.83-0.91) at 12 months, 0.77 (95% CI, 0.71-0.83) at 24 months, 0.54 (95% CI, 0.44-0.65) at 48 months, 0.60 (95% CI, 0.48-0.71) at 60 months, and 0.37 (95% CI, 0.32-0.42) at 120 months. There were no differences in proportion of success at 12 and 24 months among eyes that received Ahmed and Baerveldt tube shunts, nor between eyes with primary glaucoma, glaucoma following cataract surgery, or other secondary glaucoma. Our findings show that Ahmed and Baerveldt shunts substantially reduced IOP for at least 24 months in childhood glaucoma, with similar findings among device types and glaucoma etiologies.

Indexed as

GlaucomaGlaucoma Drainage ImplantsTrabeculectomyChildFollow-Up StudiesHumansIntraocular PressurePostoperative ComplicationsProsthesis ImplantationRetrospective StudiesTreatment OutcomeAhmed glaucoma valveBaerveldt glaucoma implantChildhood glaucomaGlaucoma drainage deviceSystematic review and meta-analysis

Identifiers

PMID36740196
PMCPMC10293048
OpenAlexW4319074006

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.