Evidence map›Paper›PMID 36740025›Full record

ReviewAlcohol (Fayetteville, N.Y.)2023

Combined exposure to alcohol and cannabis during development: Mechanisms and outcomes.

Martina V Kovács, Helenice Charchat-Fichman, J Landeira-Fernandez, Alexandre E Medina, Thomas E Krahe

Open access · greenAbstract readReview
In one paragraph

Review in Alcohol (Fayetteville, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. The Role of the Hedgehog Pathway in Alcohol-Induced Birth Defects.Advances in experimental medicine and biology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Martina V KovácsDepartamento de Psicologia, Laboratório de Neurociência do Comportamento, Pontifícia Universidade Católica do Rio de Janeiro, Rua Marquês de São Vicente, 225, Gávea - Rio de Janeiro, RJ, 22451-900, Brazil.
Helenice Charchat-FichmanDepartamento de Psicologia, Laboratório de Neurociência do Comportamento, Pontifícia Universidade Católica do Rio de Janeiro, Rua Marquês de São Vicente, 225, Gávea - Rio de Janeiro, RJ, 22451-900, Brazil.
J Landeira-FernandezDepartamento de Psicologia, Laboratório de Neurociência do Comportamento, Pontifícia Universidade Católica do Rio de Janeiro, Rua Marquês de São Vicente, 225, Gávea - Rio de Janeiro, RJ, 22451-900, Brazil.
Alexandre E MedinaDepartment of Pediatrics - School of Medicine, University of Maryland School of Medicine, Baltimore, MD, 21201, United States. Electronic address: amedina@som.umaryland.edu.
Thomas E KraheDepartamento de Psicologia, Laboratório de Neurociência do Comportamento, Pontifícia Universidade Católica do Rio de Janeiro, Rua Marquês de São Vicente, 225, Gávea - Rio de Janeiro, RJ, 22451-900, Brazil. Electronic address: tekrahe@puc-rio.br.
Pontifícia Universidade Católica do Rio de Janeiro · BRUniversity of Maryland, Baltimore · US

Funding

Amplifier Replacement for Slice Electrophysiology StudiesR01AA013023 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI MEDINA, ALEXANDRE ESTEVES · 2001 to 2021
$6.3M
A New Model of Gestational Cannabis ExposureR21DA053566 · NIDA · UNIVERSITY OF MARYLAND BALTIMORE · PI MEDINA, ALEXANDRE ESTEVES · 2021 to 2022
$425k
NIAAA NIH HHS R01 AA013023NIDA NIH HHS R21 DA053566
6 · The paper itself

Abstract

Exposure to substances of abuse during pregnancy can have long-lasting effects on offspring. Alcohol is one of the most widely used substances of abuse that leads to the most severe consequences. Recent studies in the United States, Canada, and the United Kingdom showed that between 1% and 7% of all children exhibit signs and symptoms of fetal alcohol spectrum disorder (FASD). Despite preventive campaigns, the rate of children with FASD has not decreased during recent decades. Alcohol consumption often accompanies exposure to such drugs as tobacco, cocaine, opioids, and cannabis. These interactions can be synergistic and exacerbate the deleterious consequences of developmental alcohol exposure. The present review focuses on interactions between alcohol and cannabis exposure and the potential consequences of these interactions.

Indexed as

CannabisFetal Alcohol Spectrum DisordersHallucinogensPrenatal Exposure Delayed EffectsAlcohol DrinkingCannabinoid Receptor AgonistsChildEthanolFemaleHumansPregnancyUnited StatesCannabinoid Receptor AgonistsEthanolHallucinogensCannabinoid receptorsDrug interactionsEndocannabinoid systemFetal alcohol spectrum disorders (FASD)Prenatal drug exposureSimultaneous alcohol and cannabis exposure

Identifiers

PMID36740025
PMCPMC10372841
OpenAlexW4319072695

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.