ArticleBiomedical engineering online2023
The significance of ophthalmological features in diagnosis of thyroid-associated ophthalmopathy.
Article in Biomedical engineering online, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Added value of multiparametric MRI combining dynamic contrast-enhanced and diffusion-weighted imaging for determining thyroid-associated ophthalmopathy activity.European radiology · 2026Article
- Article
- Alterations in blood flow at the optic nerve head in patients with thyroid eye disease using optic coherence tomography angiography.Frontiers in medicine · 2025Article
- Percutaneous para-levator palpebrae superioris and subconjunctival injection of triamcinolone acetonide for upper eyelid retraction in thyroid-associated ophthalmopathy.Frontiers in medicine · 2025Article
- Predictive model for the progression of inactive thyroid eye disease: a retrospective study.Endocrine · 2024Article
- Advances in artificial intelligence in thyroid-associated ophthalmopathy.Frontiers in endocrinology · 2024Review
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Authors and funding
12 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundThyroid-associated ophthalmopathy (TAO) is an autoimmune disorder. It has discriminable appearance. This study was conducted to dig the clinical significance of demographic characteristics and ophthalmologic diagram features in TAO diagnosis and stage/severity evaluation.
resultsWe included 320 males and 633 females, with an average age of 41.75 ± 13.75. A majority of TAO patients had hyperthyroidism, and most of them were in the inactive stage and at the moderate level. The thyroid function type, stage and severity were closely associated with hypopsia, eyelid congestion, conjunctival congestion, corneal ulcer, ocular motility disorder, best corrected visual acuity, and extraocular muscle thickening. Using these features, we established different logistic regression models to predict thyroid function subtypes, abnormal thyroid function, stage, and severity, in which the AUC of the ROC curve and accuracies were satisfactory.
conclusionTogether, TAO subtype, stage and severity can be diagnosed by auxiliary references including demographic factors, symptoms from complains, and image features. These non-invasive indices can be applied in a timely manner in clinical estimating TAO status.
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