Evidence map›Paper›PMID 36739363›Full record

ArticleOncogene2023

Transgenic IDH2

Dandan Wang, Lichuan Zheng, Bowie Yik Ling Cheng, Chun-Fung Sin, Runsheng Li, Sze Pui Tsui, Xinyu Yi, Alvin Chun Hang Ma, Bai Liang He, Anskar Yu Hung Leung and 1 more

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncogene, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Dandan WangDivision of Haematology, Department of Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Lichuan ZhengDivision of Haematology, Department of Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Bowie Yik Ling ChengDivision of Haematology, Department of Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Chun-Fung SinDepartment of Pathology, Queen Mary Hospital, Hong Kong SAR, China.
Runsheng LiDepartment of Infectious Diseases and Public Health, City University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0003-1563-1844
Sze Pui TsuiDepartment of Pathology, Queen Mary Hospital, Hong Kong SAR, China.
Xinyu YiBGI-Genomics, BGI-Shenzhen, Shenzhen, China.
Alvin Chun Hang MaDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, China.
Bai Liang HeGuangdong Provincial Key Laboratory of Biomedical Imaging and Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong, 519000, China.
Anskar Yu Hung LeungDivision of Haematology, Department of Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China. ayhleung@hku.hk.
Xuan SunDivision of Haematology, Department of Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China. xuansun@hku.hk.ORCID 0000-0002-3051-1720
Chinese University of Hong Kong · HKQueen Mary Hospital · CNBGI Group (China) · CNCity University of Hong Kong · HKHong Kong Polytechnic University · HKSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isocitrate dehydrogenase 2 (IDH2) mutations occur in more than 15% of cytogenetically normal acute myeloid leukemia (CN-AML) but comparative studies of their roles in leukemogenesis have been scarce. We generated zebrafish models of IDH2

Indexed as

Leukemia, Myeloid, AcuteZebrafishAdultAnimalsAnimals, Genetically ModifiedCore Binding Factor Alpha 2 Subunitfms-Like Tyrosine Kinase 3GenotypeHumansIsocitrate DehydrogenaseMutationNucleophosminCore Binding Factor Alpha 2 Subunitfms-Like Tyrosine Kinase 3Isocitrate DehydrogenaseNucleophosmin

Identifiers

PMID36739363
PMCPMC10101851
OpenAlexW4319228116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.