Evidence map›Paper›PMID 36739282›Full record

ArticleScientific data2023

Digital 3D Brain MRI Arterial Territories Atlas.

Chin-Fu Liu, Johnny Hsu, Xin Xu, Ganghyun Kim, Shannon M Sheppard, Erin L Meier, Michael I Miller, Argye E Hillis, Andreia V Faria

Abstract readDataset
In one paragraph

Article in Scientific data, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Topography and functional connectivity analysis of heart surgery-associated brain lesions: a literature review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Pooled it
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chin-Fu LiuCenter for Imaging Science, Johns Hopkins University, Baltimore, MD, USA.
Johnny HsuDepartment of Radiology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Xin XuDepartment of Radiology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Ganghyun KimCenter for Imaging Science, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0003-1116-7546
Shannon M SheppardDepartment of Communication Sciences & Disorders, Chapman University, Orange, CA, USA.
Erin L MeierDepartment of Communication Sciences & Disorders, Northeastern University, Boston, MA, USA.
Michael I MillerCenter for Imaging Science, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0003-4689-3855
Argye E HillisDepartment of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Andreia V FariaDepartment of Radiology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA. afaria1@jhmi.edu.ORCID 0000-0002-1673-002X

Funding

Telerehab for Aphasia (TERRA)P50DC014664 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI FRIDRIKSSON, JULIUS · 2016 to 2025
$25.0M
TRD 4: Platforms for multi-modal and multi-scale imaging dataP41EB031771 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Hanzhang Lu, Peter CM Van Zijl · 2021 to 2026
$9.9M
The Neural Basis of Impaired Affective Prosody in Alzheimer's Disease and Frontotemporal DegenerationR01DC015466 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI HILLIS, ARGYE E. · 2017 to 2021
$3.5M
NIBIB NIH HHS P41 EB031771NIDCD NIH HHS P50 DC014664NIDCD NIH HHS R01 DC015466
6 · The paper itself

Abstract

The locus and extent of brain damage in the event of vascular insult can be quantitatively established quickly and easily with vascular atlases. Although highly anticipated by clinicians and clinical researchers, no digital MRI arterial atlas is readily available for automated data analyses. We created a digital arterial territory atlas based on lesion distributions in 1,298 patients with acute stroke. The lesions were manually traced in the diffusion-weighted MRIs, binary stroke masks were mapped to a common space, probability maps of lesions were generated and the boundaries for each arterial territory was defined based on the ratio between probabilistic maps. The atlas contains the definition of four major supra- and infra-tentorial arterial territories: Anterior, Middle, Posterior Cerebral Arteries and Vertebro-Basilar, and sub-territories (thalamoperforating, lenticulostriate, basilar and cerebellar arterial territories), in two hierarchical levels. This study provides the first publicly-available, digital, 3D deformable atlas of arterial brain territories, which may serve as a valuable resource for large-scale, reproducible processing and analysis of brain MRIs of patients with stroke and other conditions.

Indexed as

BrainMagnetic Resonance ImagingStrokeDiffusion Magnetic Resonance ImagingHumansNeuroimaging

Identifiers

PMID36739282
PMCPMC9899211

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.