Evidence map›Paper›PMID 36738772›Full record

ArticleEnvironmental research2023

Associations between prenatal and early-life air pollution exposure and lung function in young children: Exploring influential windows of exposure on lung development.

Andreas M Neophytou, Liza Lutzker, Kristen M Good, Jennifer K Mann, Elizabeth M Noth, Stephanie M Holm, Sadie Costello, Tim Tyner, Kari C Nadeau, Ellen A Eisen and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Andreas M NeophytouDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA. Electronic address: Andreas.Neophytou@colostate.edu.
Liza LutzkerDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA, USA.
Kristen M GoodDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA; Division of Disease Control and Public Health Response, Colorado Department of Public Health and Environment, Denver, CO, USA.
Jennifer K MannDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA, USA.
Elizabeth M NothDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA, USA.
Stephanie M HolmDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA, USA; Department of Medicine, University of California, San Francisco, CA, USA.
Sadie CostelloDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA, USA.
Tim TynerUniversity of California, San Francisco-Fresno, Fresno, CA, USA; Central California Asthma Collaborative, Fresno, CA, USA.
Kari C NadeauSean N. Parker Center for Allergy and Asthma Research at Stanford University, Palo Alto, CA, USA; Department of Environmental Health. Harvard T.H. Chan School of Public Health, Boston MA, USA.
Ellen A EisenDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA, USA.
Fred LurmannSonoma Technology, Petaluma, CA, USA.
S Katharine HammondDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA, USA.
John R BalmesDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA, USA; University of California, San Francisco-Fresno, Fresno, CA, USA.
University of California, Berkeley · USUniversity of California, San Francisco · USColorado Department of Public Health and Environment · USColorado State University · USHarvard University · USSonoma Technology (United States) · US

Funding

Targeted Research Training CoreT42OH008429 · OH · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARRIS ADAMSON, CARISA · 2005 to 2024
$30.0M
UC Berkeley/Stanford Children's Enviromental Health CenterP01ES022849 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BALMES, JOHN R, HAMMOND, S KATHARINE · 2013 to 2018
$4.2M
CHAPS Cohort MaintenanceR24ES030888 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BALMES, JOHN R, HOLLAND, NINA T · 2020 to 2025
$1.9M
Air pollution exposures and children's health: mediation and interaction in a counterfactual frameworkR00ES027511 · NIEHS · COLORADO STATE UNIVERSITY · PI NEOPHYTOU, ANDREAS · 2019 to 2022
$747k
NIEHS NIH HHS P01 ES022849NIEHS NIH HHS R00 ES027511NIEHS NIH HHS R24 ES030888NIOSH CDC HHS T42 OH008429
6 · The paper itself

Abstract

backgroundEvidence in the literature suggests that air pollution exposures experienced prenatally and early in life can be detrimental to normal lung development, however the specific timing of critical windows during development is not fully understood.

objectivesWe evaluated air pollution exposures during the prenatal and early-life period in association with lung function at ages 6-9, in an effort to identify potentially influential windows of exposure for lung development.

methodsOur study population consisted of 222 children aged 6-9 from the Fresno-Clovis metro area in California with spirometry data collected between May 2015 and May 2017. We used distributed-lag non-linear models to flexibly model the exposure-lag-response for monthly average exposure to fine particulate matter (PM

resultsPM

conclusionsOur findings indicate that prenatal and early-life exposures to PM

Indexed as

Air PollutantsAir PollutionOzoneChildChild, PreschoolEnvironmental ExposureFemaleHumansLungParticulate MatterPregnancyAir PollutantsOzoneParticulate MatterAir pollutionDistributed lag-modelsInfluential windows of exposureLung function

Identifiers

PMID36738772
PMCPMC9974878
OpenAlexW4319161365

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.