Evidence map›Paper›PMID 36738650›Full record

ReviewMedical image analysis2023

Transforming medical imaging with Transformers? A comparative review of key properties, current progresses, and future perspectives.

Jun Li, Junyu Chen, Yucheng Tang, Ce Wang, Bennett A Landman, S Kevin Zhou

Abstract readReview
In one paragraph

Review in Medical image analysis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

113 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
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  6. Article
  7. Demographic Reporting and the Absence of Hispanic/Latino Representation in Dermatology Artificial Intelligence: A Scoping Review.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2026
    Article
  8. Downstream-Aware Automated QC of Images and AI-Generated Segmentations.Journal of imaging informatics in medicine · 2026
    Article
  9. Article
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  13. Review
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  20. Article

53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jun LiKey Lab of Intelligent Information Processing of Chinese Academy of Sciences (CAS), Institute of Computing Technology, CAS, Beijing 100190, China.
Junyu ChenRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutes, Baltimore, MD, USA.
Yucheng TangDepartment of Electrical and Computer Engineering, Vanderbilt University, Nashville, TN, USA.
Ce WangKey Lab of Intelligent Information Processing of Chinese Academy of Sciences (CAS), Institute of Computing Technology, CAS, Beijing 100190, China.
Bennett A LandmanDepartment of Electrical and Computer Engineering, Vanderbilt University, Nashville, TN, USA.
S Kevin ZhouKey Lab of Intelligent Information Processing of Chinese Academy of Sciences (CAS), Institute of Computing Technology, CAS, Beijing 100190, China; School of Biomedical Engineering & Suzhou Institute for Advanced Research, Center for Medical Imaging, Robotics, and Analytic Computing & Learning (MIRACLE), University of Science and Technology of China, Suzhou 215123, China. Electronic address: skevinzhou@ustc.edu.cn.

Funding

Multi-Modality Quantitiative Imaging for Evaluation of Response to Cancer TherapyU01CA140204 · NCI · JOHNS HOPKINS UNIVERSITY · PI DU, YONG, SOLNES, LILJA · 2011 to 2022
$6.1M
High Energy and Spatial Resolution Multi-Isotope SPECT Imaging of Targeted Alpha-Emitters and their DaughtersU01EB031798 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI DU, YONG, FREY, ERIC C. · 2021 to 2025
$3.8M
Hyperspectral Single Photon Imaging of Targeted Alpha-EmittersR01EB031023 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI DU, YONG, GHALY, MICHAEL · 2021 to 2024
$2.7M
NCI NIH HHS U01 CA140204NIBIB NIH HHS R01 EB031023NIBIB NIH HHS U01 EB031798
6 · The paper itself

Abstract

Transformer, one of the latest technological advances of deep learning, has gained prevalence in natural language processing or computer vision. Since medical imaging bear some resemblance to computer vision, it is natural to inquire about the status quo of Transformers in medical imaging and ask the question: can the Transformer models transform medical imaging? In this paper, we attempt to make a response to the inquiry. After a brief introduction of the fundamentals of Transformers, especially in comparison with convolutional neural networks (CNNs), and highlighting key defining properties that characterize the Transformers, we offer a comprehensive review of the state-of-the-art Transformer-based approaches for medical imaging and exhibit current research progresses made in the areas of medical image segmentation, recognition, detection, registration, reconstruction, enhancement, etc. In particular, what distinguishes our review lies in its organization based on the Transformer's key defining properties, which are mostly derived from comparing the Transformer and CNN, and its type of architecture, which specifies the manner in which the Transformer and CNN are combined, all helping the readers to best understand the rationale behind the reviewed approaches. We conclude with discussions of future perspectives.

Indexed as

Diagnostic ImagingNeural Networks, ComputerHumansMedical imagingSurveyTransformer

Identifiers

PMID36738650
PMCPMC10010286

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.