Evidence map›Paper›PMID 36738568›Full record

Observational studyThe American journal of emergency medicine2023

Association of delirium with increased short-term mortality among older emergency department patients: A cohort study.

Mariah L Arneson, Lucas Oliveira J E Silva, Jessica A Stanich, Molly M Jeffery, Heidi L Lindroth, Alexander D Ginsburg, Susan M Bower, Aidan F Mullan, Fernanda Bellolio

Abstract readObservational Study
In one paragraph

Observational study in The American journal of emergency medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Article
  12. Observational
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  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mariah L ArnesonMedical College of Wisconsin, Green Bay, WI, USA.
Lucas Oliveira J E SilvaDepartment of Emergency Medicine, Mayo Clinic, Rochester, MN, USA; Department of Emergency Medicine, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil.
Jessica A StanichDepartment of Emergency Medicine, Mayo Clinic, Rochester, MN, USA; Department of Medicine, Section of Geriatric Medicine, Mayo Clinic, Rochester, MN, USA.
Molly M JefferyDepartment of Emergency Medicine, Mayo Clinic, Rochester, MN, USA; Division of Health Care Delivery Research, Mayo Clinic, Rochester, MN, USA.
Heidi L LindrothDepartment of Nursing, Mayo Clinic, Rochester, MN, USA.
Alexander D GinsburgDepartment of Emergency Medicine, Mayo Clinic, Rochester, MN, USA; Department of Medicine, Section of Palliative Care, Mayo Clinic, Rochester, MN, USA.
Susan M BowerDepartment of Emergency Medicine, Mayo Clinic, Rochester, MN, USA; Department of Nursing, Mayo Clinic, Rochester, MN, USA.
Aidan F MullanDepartment of Quantitative Health Sciences, Division of Biostatistics and Informatics, Mayo Clinic, Rochester, MN, USA.
Fernanda BellolioDepartment of Emergency Medicine, Mayo Clinic, Rochester, MN, USA; Department of Medicine, Section of Geriatric Medicine, Mayo Clinic, Rochester, MN, USA; Division of Health Care Delivery Research, Mayo Clinic, Rochester, MN, USA. Electronic address: bellolio.fernanda@mayo.edu.

Funding

Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
NCATS NIH HHS UL1 TR002377
6 · The paper itself

Abstract

STUDY

objectiveTo evaluate the association between delirium and subsequent short-term mortality in geriatric patients presenting to the emergency department (ED).

methodsThis was an observational cohort study of adults age ≥75 years who presented to an academic ED and were screened for delirium during their ED visit. The Delirium Triage Screen followed by the Brief Confusion Assessment Method were used to ascertain the presence of delirium. In-hospital, 7-day, and 30-day mortality were compared between patients with and without ED delirium. Odds ratios with 95% confidence intervals (CIs) were calculated through logistic regression after adjusting for confounders including age, sex, history of dementia, ED disposition, and acuity.

resultsA total of 967 ED visits were included for analysis among which delirium was detected in 107 (11.1%). The median age of the cohort was 83 years (IQR 79, 88), 526 (54.4%) were female, 285 (29.5%) had documented dementia, and 171 (17.7%) had a high acuity Emergency Severity Index triage level 1 or 2. During the hospitalization, 5/107 (4.7%) of those with delirium and 4/860 (0.5%) of those without delirium died. Within 7 days of ED departure, 6/107 (5.6%) of those with delirium and 6/860 (0.7%) of those without delirium died (unadjusted OR 8.46, 95% CI 2.68-26.71). Within 30 days, 18/107 (16.8%) of those with delirium and 37/860 (4.3%) of those without delirium died (unadjusted OR 4.50, 95% CI 2.46-8.23). ED delirium remained associated with higher 7-day (adjusted OR 5.23, 95% CI 1.44-19.05, p = 0.008) and 30-day mortality (adjusted OR 2.82, 95% CI 1.45-5.46, p = 0.002).

conclusionDelirium is an important prognostic factor that ED clinicians and nurses must be aware of to optimize delirium prevention, management, disposition, and communication with patients and families.

Indexed as

DeliriumDementiaAgedCohort StudiesEmergency Service, HospitalFemaleHumansMaleProspective StudiesDeliriumElderlyEmergency departmentMortalityPrognostic

Identifiers

PMID36738568
PMCPMC10038894

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.