Evidence map›Paper›PMID 36738404›Full record

ArticleAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2023

Antioxidants encapsulated milk-derived exosomes for functional food development.

Yuhei Onizuka, Kazuya Fujita, Sachiko Ide, Toyohiro Naito, Noritada Kaji

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yuhei OnizukaDepartment of Applied Chemistry, Graduate School of Engineering, Kyushu University, Fukuoka, Japan.
Kazuya FujitaDepartment of Applied Chemistry, Graduate School of Engineering, Kyushu University, Fukuoka, Japan.
Sachiko IdeDepartment of Applied Chemistry, Graduate School of Engineering, Kyushu University, Fukuoka, Japan.
Toyohiro NaitoDepartment of Applied Chemistry, Graduate School of Engineering, Kyushu University, Fukuoka, Japan.
Noritada KajiDepartment of Applied Chemistry, Graduate School of Engineering, Kyushu University, Fukuoka, Japan. kaji@cstf.kyushu-u.ac.jp.ORCID http://orcid.org/0000-0002-9828-873X
Kyushu University · JP

Funding

Japan Science and Technology Corporation JPMJPF2107Japan Society for the Promotion of Science London 19KK0140Japan Society for the Promotion of Science London 21H01966
6 · The paper itself

Abstract

Reactive oxygen species are known to be involved in various diseases, and antioxidant ingredients are expected to essentially prevent diseases and contribute to improving health. However, antioxidants are easily degraded by enzymes before being absorbed in the intestine, so a means of transport that prevents their degradation in the body is necessary. Exosomes, which play an important role in communication between individual cells, have attracted attention as a new transport carrier of miRNA and DNA, but not yet fully exploited in food research. More recently, exosomes extracted from bovine milk began to be widely used as a cost-effective transport carrier not in clinical medicine but also in functional food materials. To develop practical applications as carriers for functional foods, systematic studies are necessary to clarify the introduction efficiency and the properties of encapsulated substances. In this study, we applied electroporation and incubation to encapsulate antioxidants into the exosomes and studied the encapsulation efficiency into the exosomes and the anticancer activity.

Indexed as

ExosomesMicroRNAsAnimalsAntioxidantsFunctional FoodMilkAntioxidantsMicroRNAsAntioxidantsFunctional foodsMilk-derived exosomes

Identifiers

PMID36738404
OpenAlexW4319216304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.